Locascio Antonella, Blázquez Miguel A, Alabadí David
Instituto de Biología Molecular y Celular de Plantas-CSIC-U. Politécnica de Valencia, Valencia, Spain.
Plant Cell Physiol. 2013 Aug;54(8):1229-37. doi: 10.1093/pcp/pct082. Epub 2013 Jun 18.
Changes in gene expression are the main outcome of hormone signaling cascades that widely control plant physiology. In the case of the hormones gibberellins, the transcriptional control is exerted through the activity of the DELLA proteins, which act as negative regulators in the signaling pathway. This review focuses on recent transcriptomic approaches in the context of gibberellin signaling, which have provided useful information on new processes regulated by these hormones such as the regulation of photosynthesis and gravitropism. Moreover, the enrichment of specific cis-elements among DELLA primary targets has also helped extend the view that DELLA proteins regulate gene expression through the interaction with multiple transcription factors from different families.
基因表达的变化是广泛控制植物生理的激素信号级联反应的主要结果。就赤霉素而言，转录控制是通过DELLA蛋白的活性来实现的，DELLA蛋白在信号通路中作为负调节因子发挥作用。本综述聚焦于赤霉素信号传导背景下的最新转录组学方法，这些方法为这些激素调控的新过程（如光合作用和向地性的调控）提供了有用信息。此外，DELLA主要靶标中特定顺式元件的富集也有助于拓展这样一种观点，即DELLA蛋白通过与来自不同家族的多种转录因子相互作用来调节基因表达。
