手性季碳中心α,β-不饱和 γ-氨基酯的铑催化 N-乙酰-α-芳基胺与丙烯酸酯的 codimerization 合成。
Synthesis of α,β-unsaturated γ-amino esters with a quaternary center by ruthenium-catalyzed codimerization of N-acetyl α-arylenamines and acrylates.
机构信息
State Key Laboratory and Institute of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071, China.
出版信息
Org Biomol Chem. 2012 Jan 7;10(1):43-5. doi: 10.1039/c1ob06412f. Epub 2011 Sep 26.
PMID:21953006
Abstract
Ruthenium-catalyzed highly selective codimerization of N-acetyl α-arylenamines with ethyl acrylates is reported. This codimerization reaction provides a new efficient method for the synthesis of α,β-unsaturated γ-amino esters with a quaternary center.
摘要
报道了钌催化的 N-乙酰-α-芳基胺与丙烯酸乙酯的高选择性 codimerization。该 codimerization 反应为合成具有季碳原子的α,β-不饱和γ-氨基酯提供了一种新的有效方法。
Zotero 插件