Huang Yu-Chieh, Wu Chen-Te, Lin Gigin, Chuang Wen-Yu, Yeow Kee-Min, Wan Yung-Liang
Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou, College of Medicine, Chang Gung University, 5 Fushing Road, Taoyuan, Taiwan.
J Clin Ultrasound. 2012 May;40(4):189-94. doi: 10.1002/jcu.20873. Epub 2011 Sep 23.
To retrospectively compare the accuracies of ultrasound-guided fine-needle aspiration (USFNA) and ultrasound-guided core needle biopsy (USCNB) in the diagnosis of parotid masses.
A total of 171 patients (aged 17-86 years, mean 54 years) with parotid masses (35 malignant and 136 benign lesions) underwent either USFNA (n = 107) or USCNB (n = 64). The diagnostic accuracies for differentiating benign from malignant lesions of both examinations were compared. Surgical histopathology (n = 104) and clinical diagnosis (n = 67) were used to establish the final diagnoses.
USCNB had a significantly higher sensitivity (94.1%) than USFNA (55.6%) (p < 0.05) in differentiating benign lesions from malignant conditions. The specificity and overall accuracy of USCNB were higher than those of USFNA (100% and 98.4% versus 93.3% and 86.9%, respectively). USCNB provided more specific diagnosis than USFNA (100% versus 93.3%, p < 0.05). All six patients with lymphomas who underwent USCNB were accurately diagnosed, whereas all four patients with lymphomas who underwent USFNA were not.
USCNB should be preferred to USFNA when a definite diagnosis of a parotid solid mass is needed.
回顾性比较超声引导下细针穿刺抽吸术(USFNA)和超声引导下粗针穿刺活检术(USCNB)在腮腺肿块诊断中的准确性。
共有171例腮腺肿块患者(年龄17 - 86岁,平均54岁),其中35例为恶性病变,136例为良性病变,接受了USFNA(n = 107)或USCNB(n = 64)检查。比较两种检查区分良性和恶性病变的诊断准确性。采用手术组织病理学(n = 104)和临床诊断(n = 67)来确定最终诊断。
在区分良性病变和恶性病变方面,USCNB的敏感性(94.1%)显著高于USFNA(55.6%)(p < 0.05)。USCNB的特异性和总体准确性高于USFNA(分别为100%和98.4%,而USFNA为93.3%和86.9%)。USCNB比USFNA提供了更具特异性的诊断(100%对93.3%,p < 0.05)。所有6例接受USCNB的淋巴瘤患者均被准确诊断,而所有4例接受USFNA的淋巴瘤患者均未被准确诊断。
当需要对腮腺实性肿块进行明确诊断时,应优先选择USCNB而非USFNA。