Poisonous Plant Research Laboratory, Agricultural Research Service, United States Department of Agriculture, 1150 E. 1400 N., Logan, Utah 84341, USA.
Phytochem Anal. 2012 May-Jun;23(3):278-84. doi: 10.1002/pca.1355. Epub 2011 Sep 26.
Many species in the Lupinus genus are poorly defined morphologically, potentially resulting in improper taxonomic identification. Lupine species may contain quinolizidine and/or piperidine alkaloids that can be acutely toxic and/or teratogenic, the latter resulting in crooked calf disease.
To identify characteristic alkaloid profiles of Lupinus sabinianus, L. garfieldensis and L. sericeus which would aid in discriminating these species from each other and from L. sulphureus.
Quinolizidine and piperidine alkaloids were extracted from herbarium specimens and recent field collections of L. sabinianus, L. garfieldensis and L. sericeus. The alkaloid composition of each species was defined using GC-FID and GC-MS and compared using multivariate statistics.
Each of the three species investigated contained a diagnostic chemical fingerprint composed of quinolizidine and/or piperidine alkaloids.
The alkaloid profiles of Lupinus sabinianus, L. garfieldensis and L. sericeus can be used as a tool to discriminate these species from each other and L. sulphureus as long as one considers locality of the collection in the case of L. sabinianus.
卢比纳属的许多物种在形态上定义不明确，可能导致分类鉴定不当。羽扇豆属的物种可能含有喹诺里西啶和/或哌啶生物碱，这些生物碱可能具有急性毒性和/或致畸性，后者会导致畸形小牛病。
确定沙比纳羽扇豆、加菲尔德羽扇豆和丝质羽扇豆的特征性生物碱图谱，以帮助区分这些物种彼此之间以及与硫代羽扇豆的区别。
从标本和最近采集的沙比纳羽扇豆、加菲尔德羽扇豆和丝质羽扇豆的实地采集样本中提取喹诺里西啶和哌啶生物碱。使用 GC-FID 和 GC-MS 定义每种物种的生物碱组成，并使用多元统计进行比较。
所研究的三个物种均含有由喹诺里西啶和/或哌啶生物碱组成的诊断性化学指纹图谱。
只要考虑到沙比纳羽扇豆采集地点的情况，沙比纳羽扇豆、加菲尔德羽扇豆和丝质羽扇豆的生物碱图谱可以作为区分这些物种彼此以及与硫代羽扇豆的工具。
