Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
G Ital Dermatol Venereol. 2011 Oct;146(5):341-52.
Advances in transplant surgery and more effective immunosuppressive regimen have led to increased survival rates among transplant recipients. However, intense immunosuppression has led to increased rates of both internal and cutaneous malignancies, with skin cancer occurring as the most common cancer after transplantation. While many transplant recipients will develop mild and manageable cutaneous malignancies, some will develop potentially life-threatening disease. Dermatologists are an integral part in the care of organ transplant recipients. Therefore, it is important for dermatologists to be familiar with the available epidemiological data and management of skin cancers in this patient population. In this paper, we review the risk factors, prevention, recognition and effective intervention of skin cancers in organ transplant recipients.
移植手术的进步和更有效的免疫抑制方案导致移植受者的生存率提高。然而，强烈的免疫抑制导致内部和皮肤恶性肿瘤的发生率增加，皮肤癌是移植后最常见的癌症。虽然许多移植受者会出现轻度且可控制的皮肤恶性肿瘤，但有些受者会出现潜在的威胁生命的疾病。皮肤科医生是器官移植受者护理的重要组成部分。因此，皮肤科医生熟悉该患者人群的皮肤癌的可用流行病学数据和管理非常重要。在本文中，我们回顾了器官移植受者皮肤癌的危险因素、预防、识别和有效干预。
