以分子氧为氧化剂的水中氧化交叉脱氢偶联反应：钒催化的四氢异喹啉吲哚化反应。
An oxidative cross-dehydrogenative-coupling reaction in water using molecular oxygen as the oxidant: vanadium catalyzed indolation of tetrahydroisoquinolines.
机构信息
Department of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, Karnataka, India.
出版信息
Chem Commun (Camb). 2011 Nov 14;47(42):11787-9. doi: 10.1039/c1cc15050b. Epub 2011 Sep 28.
PMID:21956547
Abstract
An aerobic oxidative cross-dehydrogenative coupling reaction between sp(3) C-H and sp(2) C-H bonds is developed by employing a vanadium catalyst (10 mol%) in an aqueous medium using molecular oxygen as the oxidant. This environmentally benign strategy exhibits larger substrate scope and shows high regioselectivity.
摘要
发展了一种在环境友好的水相中，以分子氧为氧化剂，通过钒催化剂（10 mol%）实现 sp(3) C-H 和 sp(2) C-H 键间的有氧氧化交叉脱氢偶联反应。该策略具有广泛的底物适用性，并表现出很高的区域选择性。
Zotero 插件