Wicht F, Preisig R
Institut für Klinische Pharmakologie, Universität Bern.
Ther Umsch. 1990 May;47(5):364-9.
The treatment of patients suffering from alcoholism is notoriously difficult. Ambulatory supportive therapy using disulfiram and supervised by the practicing physician has many advantages. Foremost among these is the maintenance of the patient within his working and social environment. For achievement of longterm abstinence, psychological aspects (patients motivation and agreement, understanding care by the physician) may be more important than the aversive effects of disulfiram. Although disulfiram is generally a safe drug, careful preliminary work-up represents the key to proper assessment of risk versus benefit.
治疗酗酒患者的难度众所周知。由执业医师监督使用双硫仑进行门诊支持性治疗有诸多优点。其中最主要的是能让患者维持在其工作和社交环境中。对于实现长期戒酒而言，心理因素（患者的动机和认同、对医生关怀的理解）可能比双硫仑的厌恶效应更为重要。虽然双硫仑总体上是一种安全的药物，但仔细的初步检查是正确评估风险与益处的关键。
