Grishchenko S V, Borkhunova E N, Filatova I A, Vissarionova I V
Adv Gerontol. 2011;24(2):331-9.
Morphological study of eyelid biopsy tissues with varying degrees of age-related changes revealed sclerosis, infiltration, expansion and the convoluted configuration of the walls of blood vessels, stasis, reflecting microcirculation disturbance in the skin. Decrease in elasticity, elasticity and skin turgor in aging eyelids is largely due to the thinning, randomly distributed bundles of collagen and a decrease in the number or total absence of elastic fibers. In 31 patients with blepharohalasis laser Doppler flowmetry revealed a failure in the neuromuscular regulation of vascular tone, which is a manifestation of chronic stagnation in the microcirculatory bed. Revealed changes in the morphological structure of eyelid skin and microcirculatory bed confirm the trophic disturbances and congestion occurring in the skin of eyelids with aging.
对具有不同程度年龄相关性变化的眼睑活检组织进行的形态学研究显示,存在硬化、浸润、血管壁扩张和迂曲形态、淤血,反映出皮肤微循环障碍。衰老眼睑的弹性、弹性和皮肤张力下降在很大程度上是由于胶原纤维束变薄、随机分布以及弹性纤维数量减少或完全缺失。在31例睑皮松弛症患者中,激光多普勒血流仪显示血管张力的神经肌肉调节功能失效,这是微循环床慢性淤血的一种表现。眼睑皮肤和微循环床形态结构的变化证实了随着年龄增长眼睑皮肤出现的营养障碍和淤血。