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在鸡胚中培养的不同黏液病毒和副黏液病毒包膜中宿主抗原的研究。

Study of host antigens in the envelopes of different myxo- and paramyxoviruses cultivated in the embryonated hen egg.

作者信息

Ghyka G, Samuel I, Portocală R

出版信息

Virologie. 1978 Oct-Dec;29(4):259-62.

PMID:219591
Abstract

By immunoelectrophoretic analysis it was shown that different viruses--such as myxo- (influenza A0PR8) and paramyxoviruses (Sendai, SV5, NDV, mumps)--cultivated in the same host cells (chorioallantoic membranes) incorporate similar host antigens into their envelopes. The amount of host cell antigens incorporated into the virus envelopes differs from one virus to another. The fact that incorporation of host cell antigens occurs only after a virus-induced modification seems to be a general characteristic of enveloped viruses such as myxo- and paramyxoviruses.

摘要

通过免疫电泳分析表明,在相同宿主细胞(绒毛尿囊膜)中培养的不同病毒,如黏液病毒(甲型流感病毒A0PR8)和副黏病毒(仙台病毒、SV5、新城疫病毒、腮腺炎病毒),会将相似的宿主抗原整合到它们的包膜中。整合到病毒包膜中的宿主细胞抗原量因病毒而异。宿主细胞抗原的整合仅在病毒诱导的修饰之后发生,这一事实似乎是黏液病毒和副黏病毒等包膜病毒的普遍特征。

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