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单孔腹腔镜全腹部结肠切除术治疗难治性溃疡性结肠炎。

Single-incision laparoscopic total abdominal colectomy for refractory ulcerative colitis.

机构信息

Department of Surgery, University of Chicago Medical Center, 5841 S. Maryland Ave, MC 5095, Chicago, IL 60637, USA.

出版信息

Surg Endosc. 2012 Mar;26(3):862-8. doi: 10.1007/s00464-011-1925-5. Epub 2011 Sep 30.

Abstract

BACKGROUND

A three-stage restorative proctocolectomy with ileal pouch-anal anastomosis is the treatment of choice for the particularly debilitated patient with medically refractory ulcerative colitis (UC). Laparoscopic surgery has been shown to offer several advantages over the open approach in this setting. Single-incision laparoscopic surgery is an emerging minimally invasive strategy representing a truly scarless procedure for the first surgical step, namely, the total abdominal colectomy (TAC).

METHODS

Nine consecutive patients with medically refractory UC underwent a single-incision laparoscopic TAC between May and October 2010. All patients were on aggressive medical therapy with corticosteroids or immunosuppressors and were selected for this approach on the basis of their body habitus and the absence of relevant comorbidities. The whole operation was performed through a single access to the abdominal cavity, placed at the ostomy site marked preoperatively.

RESULTS

Mean operating time was 142 ± 23 min, with an estimate blood loss of 108 ± 125 ml. No intraoperative complications or conversions to conventional laparoscopy or open surgery occurred. In all cases the postoperative course was uneventful. The return of bowel function was observed on postoperative day 1.7 ± 0.7, and patients could tolerate a solid diet on postoperative day 3 ± 0.5. The mean postoperative length of stay was 5.2 ± 1.3 days.

CONCLUSIONS

In our experience, a single-incision laparoscopic approach to total abdominal colectomy for refractory ulcerative colitis has been shown to be safe and feasible. Initial results suggest that this technique can lead to improvements in short-term outcomes in selected patients.

摘要

背景

对于患有药物难治性溃疡性结肠炎(UC)且身体状况特别虚弱的患者,三阶段修复性直肠结肠切除术联合回肠袋肛管吻合术是首选治疗方法。腹腔镜手术已被证明在这种情况下比开放手术具有多项优势。单切口腹腔镜手术是一种新兴的微创策略,代表了首次手术步骤(即全腹部结肠切除术)的真正无疤痕手术。

方法

2010 年 5 月至 10 月期间,9 例患有药物难治性 UC 的患者接受了单切口腹腔镜全腹部结肠切除术。所有患者均接受了皮质类固醇或免疫抑制剂的积极药物治疗,并根据其体型和无相关合并症选择了这种方法。整个手术通过一个进入腹腔的单一通道进行,该通道位于术前标记的造口部位。

结果

平均手术时间为 142 ± 23 分钟,估计失血量为 108 ± 125ml。无术中并发症或转为常规腹腔镜或开放手术。所有病例的术后过程均平稳。术后第 1.7 ± 0.7 天恢复肠道功能,术后第 3 ± 0.5 天患者可耐受固体饮食。平均术后住院时间为 5.2 ± 1.3 天。

结论

根据我们的经验,对于难治性溃疡性结肠炎,单切口腹腔镜全腹部结肠切除术是安全可行的。初步结果表明,这种技术可以改善选定患者的短期结果。

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