Jones Siân, O'Donovan Peter, Toub David
Department of Obstetrics and Gynaecology, Bradford Royal Infirmary, Duckworth Lane, Bradford BD9 6RJ, UK.
Obstet Gynecol Int. 2012;2012:194839. doi: 10.1155/2012/194839. Epub 2011 Sep 27.
The use of thermal energy-based systems to treat uterine fibroids has resulted in a plethora of devices that are less invasive and potentially as effective in reducing symptoms as traditional options such as myomectomy. Most thermal ablation devices involve hyperthermia (heating of tissue), which entails the conversion of an external electromagnetic or ultrasound waves into intracellular mechanical energy, generating heat. What has emerged from two decades of peer-reviewed research is the concept that hyperthermic fibroid ablation, regardless of the thermal energy source, can create large areas of necrosis within fibroids resulting in reductions in fibroid volume, associated symptoms and the need for reintervention. When a greater percentage of a fibroid's volume is ablated, symptomatic relief is more pronounced, quality of life increases, and it is more likely that such improvements will be durable. We review radiofrequency ablation (RFA), one modality of hyperthermic fibroid ablation.
使用基于热能的系统治疗子宫肌瘤已催生了大量设备，这些设备侵入性较小，在减轻症状方面可能与诸如子宫肌瘤切除术等传统方法一样有效。大多数热消融设备都涉及热疗（组织加热），即将外部电磁波或超声波转化为细胞内机械能以产生热量。经过二十年同行评审研究得出的概念是，无论热能来源如何，热疗性子宫肌瘤消融都可在肌瘤内形成大面积坏死，从而导致肌瘤体积缩小、相关症状减轻以及再次干预需求减少。当肌瘤更大比例的体积被消融时，症状缓解会更明显，生活质量提高，而且这种改善更有可能持久。我们将回顾热疗性子宫肌瘤消融的一种方式——射频消融（RFA）。
