Department of Medical Imaging, School of Medical Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.
Department of Radiology, Korle Bu Teaching Hospital, Accra, Ghana.
PLoS One. 2023 Mar 16;18(3):e0283201. doi: 10.1371/journal.pone.0283201. eCollection 2023.
Uterine fibroids are benign tumors that grow in or on the uterus of women. Globally, they occur in more than 80% of women of African ancestry and 70% in white women. Uterine fibroid requires much attention because of its high incidence rate among women of all races and ages. This study sought to document the age of first diagnosis and incidence rates of uterine fibroids in our urban setting.
This study reviewed and analyzed the ages and year of diagnosis of all 2,469 patients with the first diagnosis of uterine fibroids from 1st January 2018 to 31st December 2021 in South-Central Ghana. The obtained data were analyzed using GNU PSPP, Python on Jupyter Notebook and Libre Office Calc with statistical significance level set at p≤0.05.
The overall average age was 36.29±8.08 years, with age range 17-61 years and the age groups with the highest frequencies were 35-39 years (n = 642, 26.00%), 30-34 years (n = 563, 22.80%) and 40-44 years (n = 381, 15.43%). The mean ages of the patients in 2018, 2019, 2020 and 2021 were 36.70±8.00 years (95%CI = 35.97-37.43), 37.07±7.66 years (95%CI = 36.45-37.70), 35.92±7.87 years (95%CI = 35.30-36.53) and 35.78±8.54 years (95%CI = 35.19-36.38) respectively. The incidence rate (per 100,000) of uterine fibroids in 2018, 2019, 2020 and 2021 were 66.77 (95% CI = 60.63-72.90), 81.86 (95%CI = 75.19-88.58), 85.60 (95%CI = 78.85-92.35) and 92.40 (95%CI = 85.88-98.92) respectively, with 35-39 age group recording the highest in all years.
The incidence rate of uterine fibroids increased as the years progressed and it is mostly high in 35-39 years age category, with a decreasing annual mean age trend indicative of early diagnosis.
子宫肌瘤是一种生长在女性子宫内或子宫上的良性肿瘤。在全球范围内，超过 80%的非裔美国女性和 70%的白人女性患有子宫肌瘤。由于子宫肌瘤在所有种族和年龄段的女性中的发病率都很高，因此需要引起高度重视。本研究旨在记录我们城市环境中子宫肌瘤的首次诊断年龄和发病率。
本研究回顾分析了 2018 年 1 月 1 日至 2021 年 12 月 31 日期间，加纳中南部地区首次诊断为子宫肌瘤的 2469 名患者的年龄和诊断年份。使用 GNU PSPP、Jupyter Notebook 上的 Python 和 Libre Office Calc 对获得的数据进行分析，统计显著性水平设置为 p≤0.05。
总体平均年龄为 36.29±8.08 岁，年龄范围为 17-61 岁，年龄组中频率最高的是 35-39 岁（n = 642，26.00%）、30-34 岁（n = 563，22.80%）和 40-44 岁（n = 381，15.43%）。2018 年、2019 年、2020 年和 2021 年患者的平均年龄分别为 36.70±8.00 岁（95%CI = 35.97-37.43）、37.07±7.66 岁（95%CI = 36.45-37.70）、35.92±7.87 岁（95%CI = 35.30-36.53）和 35.78±8.54 岁（95%CI = 35.19-36.38）。2018 年、2019 年、2020 年和 2021 年子宫肌瘤的发病率（每 100,000 人）分别为 66.77（95% CI = 60.63-72.90）、81.86（95%CI = 75.19-88.58）、85.60（95%CI = 78.85-92.35）和 92.40（95%CI = 85.88-98.92），所有年份中 35-39 岁年龄组的发病率最高。
子宫肌瘤的发病率随着时间的推移而增加，在 35-39 岁年龄组中发病率最高，且呈逐年平均年龄下降趋势，表明早期诊断率提高。
