Division of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta Georgia, USA.
Popul Health Metr. 2011 Sep 30;9:54. doi: 10.1186/1478-7954-9-54.
Appalachia is a region of the United States noted for the poverty and poor health outcomes of its residents. Residents of the poorest Appalachian counties have a high prevalence of diabetes and risk factors (obesity, low income, low education, etc.) for type 2 diabetes. However, diabetes prevalence exceeds what these risk factors alone explain. Based on this, the history of poor health outcomes in Appalachia, and personally observed high rates of childhood obesity and lack of concern about prediabetes, we speculated that people in Appalachia with diagnosed diabetes might tend to be diagnosed younger than their non-Appalachian counterparts.
We used data from the Behavioral Risk Factor Surveillance System (2006-2008). We compared age at diagnosis among counties by Appalachian Regional Commission-defined level of economic development. To account for risk differences, we constructed a model for average age at diagnosis of diabetes, adjusting for county economic development, obesity, income, sedentary lifestyle, and other covariates.
After adjustment for risk factors for diabetes, people in distressed or at-risk counties (the least economically developed) had their diabetes diagnosed two to three years younger than comparable people in non-Appalachian counties. No significant differences between non-Appalachian counties and Appalachian counties at higher levels of economic development remained after adjusting.
People in distressed and at-risk counties have poor access to care, and are unlikely to develop diabetes at the same age as their non-Appalachian counterparts but be diagnosed sooner. Therefore, people in distressed and at-risk counties are likely developing diabetes at younger ages. We recommend that steps to reduce health disparities between the poorest Appalachian counties and non-Appalachian counties be considered.
阿巴拉契亚地区是美国的一个区域,以其居民的贫困和健康状况不佳而闻名。最贫困的阿巴拉契亚县的居民患有糖尿病和 2 型糖尿病的风险因素(肥胖、低收入、低教育等)的患病率很高。然而,糖尿病的患病率超过了这些风险因素单独解释的范围。基于此,阿巴拉契亚地区历史上健康状况不佳,以及个人观察到的儿童肥胖率高和对糖尿病前期缺乏关注,我们推测阿巴拉契亚地区患有确诊糖尿病的人可能比非阿巴拉契亚地区的人更早被诊断出来。
我们使用了来自行为风险因素监测系统的数据(2006-2008 年)。我们比较了阿巴拉契亚地区委员会定义的经济发展水平不同的县的诊断年龄。为了考虑风险差异,我们构建了一个用于调整糖尿病平均诊断年龄的模型,调整了县经济发展、肥胖、收入、久坐不动的生活方式和其他协变量。
在调整了糖尿病的风险因素后,处于贫困或风险县(最不发达)的人比非阿巴拉契亚县的同龄人提前两到三年被诊断出患有糖尿病。在调整后,非阿巴拉契亚县和经济发展水平较高的阿巴拉契亚县之间没有明显的差异。
处于贫困和风险县的人获得医疗保健的机会较差,他们不太可能与非阿巴拉契亚县的同龄人在相同的年龄发展为糖尿病,但会更早被诊断出来。因此,贫困和风险县的人可能在更年轻时就患上了糖尿病。我们建议考虑采取措施减少最贫困的阿巴拉契亚县和非阿巴拉契亚县之间的健康差距。