Department of Epidemiology & Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.
Obstet Gynecol Clin North Am. 2011 Sep;38(3):441-54. doi: 10.1016/j.ogc.2011.05.003.
This review summarizes the published literature on the potentially circular relationship between adiposity and the menopause. Although data are limited, current information suggests there are substantial effects of obesity and adiposity on the magnitude of hormone changes experienced during the transition, as well as on the risks of chronic disease resulting from the menopause transition. However, evidence regarding the reverse, namely, effects of the menopause transition and its associated hormone changes on weight gain and redistribution of body fat, are inconclusive.
这篇综述总结了已发表的关于肥胖与绝经之间潜在循环关系的文献。尽管数据有限,但目前的信息表明,肥胖和体脂对过渡期间激素变化的幅度以及绝经过渡引起的慢性疾病风险有很大影响。然而,关于相反的情况,即绝经过渡及其相关激素变化对体重增加和体脂肪分布的影响的证据尚无定论。