Novartis Institutes for BioMedical Research, Cambridge, MA 02139, USA.
Cell. 2011 Sep 30;147(1):26-31. doi: 10.1016/j.cell.2011.09.016.
In the era of next-generation sequencing, there are significant challenges to harnessing cancer genome information to develop novel therapies. Key research thrusts in both academia and industry will speed this transition, and lessons learned for cancer will more broadly shape the process for genetic contributions to the therapy of disease more broadly.
在下一代测序时代,利用癌症基因组信息开发新疗法面临重大挑战。学术界和工业界的主要研究重点将加速这一转变,而癌症领域获得的经验教训将更广泛地推动基因贡献治疗疾病的进程。