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1.5T 磁共振体线圈内位置函数的解剖校正儿童和成人模型中的局部 SAR 增强。

Local SAR enhancements in anatomically correct children and adult models as a function of position within 1.5 T MR body coil.

机构信息

IT'IS Foundation, Zurich, Switzerland.

出版信息

Prog Biophys Mol Biol. 2011 Dec;107(3):428-33. doi: 10.1016/j.pbiomolbio.2011.09.017. Epub 2011 Sep 22.

Abstract

Usage of magnetic resonance imaging (MRI) is continuously increasing due to its excellent soft-tissue contrast and improving diagnostic values. MRI also has the advantage that it operates without ionizing radiation. The main safety concerns are torque, acceleration by the static field, nerve stimulation by the gradient fields, and tissue heating by the radio-frequency (RF) fields. This paper investigates if children and fetuses are at higher risks than adults when the current RF regulations are applied. We analyzed and compared local absorption hotspots, i.e., the peak spatial specific absorption rate averaged over any 10 g (psSAR10g) for five adults, three children of ages 5, 11 and 14 years, and 1 pregnant female (36 weeks' gestation) in 10 different Z-positions (head to calves). In the First Level Operating Mode (4 W/kg whole-body averaged exposure), the psSAR10g values found for adults were as large as 60 W/kg in the trunk and 104 W/kg in the extremities. The corresponding values for children were 43 and 58 W/kg, respectively, and 14 W/kg for the unborn child. Modeling of worst case anatomical RF loops can substantially increase the psSAR10g values, i.e., by factor >>2. The results suggest that local exposure for children and fetuses is smaller than for adults (15-75%), i.e., no special considerations for children and the unborn child are needed regarding psSAR10g due to RF. However, the local thermal load of the unborn may be significantly increased due to the high exposure average (up to 4 W/kg) of the non-perfused amniotic fluid.

摘要

由于磁共振成像(MRI)具有出色的软组织对比度和不断提高的诊断价值,其应用不断增加。MRI 的优点是它在没有电离辐射的情况下运行。主要的安全问题是扭矩、静磁场的加速度、梯度场的神经刺激以及射频(RF)场的组织加热。本文研究了当应用当前的 RF 法规时,儿童和胎儿是否比成年人面临更高的风险。我们分析并比较了五个成年人、三个年龄分别为 5、11 和 14 岁的儿童和一个怀孕女性(36 周妊娠)在 10 个不同 Z 位置(头部至小腿)的局部吸收热点,即任何 10 克的峰值空间比吸收率(psSAR10g)的平均值。在第一级操作模式(全身平均 4 W/kg 暴露)下,成年人在躯干中的 psSAR10g 值高达 60 W/kg,在四肢中的值高达 104 W/kg。儿童的相应值分别为 43 和 58 W/kg,而未出生婴儿的值为 14 W/kg。最坏情况解剖 RF 环路的建模可以大大增加 psSAR10g 值,即增加 >>2 倍。结果表明,儿童和胎儿的局部暴露小于成年人(15-75%),即由于 RF,儿童和未出生婴儿的 psSAR10g 不需要特别考虑。然而,由于非灌注羊水的高暴露平均值(高达 4 W/kg),未出生婴儿的局部热负荷可能会显著增加。

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