Anwar Hamed Mofeez, El-Danasoury Alaa M, Hashem Ayman Nasr
Magrabi Eye Hospital, Jeddah, Saudi Arabia.
Clin Ophthalmol. 2011;5:1277-80. doi: 10.2147/OPTH.S24532. Epub 2011 Sep 7.
To report the use of corneal collagen crosslinking in the treatment of infective keratitis not responding to antimicrobial therapy.
Two retrospective case reports of infective keratitis treated with corneal collagen crosslinking.
In both cases, corneal collagen crosslinking caused a rapid resolution of the infective keratitis, leaving residual stromal scarring. Due to the density of scarring, one case required subsequent penetrating keratoplasty for visual rehabilitation.
Corneal collagen crosslinking is a promising new technique for the management of infective keratitis not responding to antimicrobial therapy. Further elucidation of its safety and role in management of infectious keratitis is needed by way of future studies.
报告角膜胶原交联在治疗对抗菌治疗无反应的感染性角膜炎中的应用。
两篇关于用角膜胶原交联治疗感染性角膜炎的回顾性病例报告。
在这两个病例中，角膜胶原交联使感染性角膜炎迅速消退，留下残余基质瘢痕。由于瘢痕密度，其中1例随后需要进行穿透性角膜移植术以恢复视力。
角膜胶原交联是治疗对抗菌治疗无反应的感染性角膜炎的一种有前景的新技术。未来研究需要进一步阐明其安全性及其在感染性角膜炎治疗中的作用。
