角膜交联术后的角膜炎
keratitis after corneal crosslinking.
作者信息
McGirr Samantha, Andersen Dallin, Halgren John
机构信息
Department of Ophthalmology, Truhlsen Eye Institute at the University of Nebraska Medical Center, 3902 Leavenworth St, Omaha, NE, 68105, USA.
出版信息
Am J Ophthalmol Case Rep. 2020 Jan 31;17:100616. doi: 10.1016/j.ajoc.2020.100616. eCollection 2020 Mar.
PURPOSE
To report a case of fungal keratitis after corneal collagen crosslinking (CXL) surgery.
OBSERVATIONS
We report a case of fungal keratitis after CXL for post-refractive surgery ectasia. The patient presented 12 days after surgery with a corneal ulcer that was culture positive for species of fungus. She subsequently developed a bacterial superinfection. The keratitis resolved with medical therapy, although the patient required a penetrating keratoplasty (PKP) due to central corneal scarring.
CONCLUSIONS AND IMPORTANCE
To our knowledge, this is the first case of fungal keratitis as a complication after CXL in the United States and the first case of infection after CXL using the Dresden protocol. Infectious keratitis is a rare but serious complication of CXL, and we suggest continued innovation of operative techniques that may reduce the risk of infectious keratitis.
目的
报告1例角膜胶原交联（CXL）手术后发生真菌性角膜炎的病例。
观察结果
我们报告1例因屈光手术后角膜扩张而行CXL术后发生真菌性角膜炎的病例。患者术后12天出现角膜溃疡，真菌培养阳性。随后她发生了细菌二重感染。尽管患者因中央角膜瘢痕需要行穿透性角膜移植术（PKP），但经药物治疗后角膜炎得以消退。
结论与意义
据我们所知，这是美国首例CXL术后发生真菌性角膜炎的病例，也是首例使用德累斯顿方案行CXL术后发生感染的病例。感染性角膜炎是CXL罕见但严重的并发症，我们建议持续创新手术技术以降低感染性角膜炎的风险。
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