Nascimento Jeferson C, Barbosa Luiz C A, Paula Vanderlucia F, David Jorge M, Fontana Renato, Silva Luiz A M, França Robson S
Departamento de Química e Exatas, Universidade Estadual do Sudoeste da Bahia, UESB, Jequié, BA, Brasil.
An Acad Bras Cienc. 2011 Sep;83(3):787-99. doi: 10.1590/s0001-37652011005000019.
This work describes the chemical composition and antimicrobial activity of the volatile oils of Ocimum canum and Ocimum selloi, both occurring in Jequié/BA, northeastern Brazil. The plants were collected in the winter/2005 and summer/2006, the oils extracted by steam distillation and further analyzed by GC-MS. A total of 30 and 31 compounds was identified from the oils of O. selloi and O. canum, respectively. It was observed that the oil content of O. canum showed variation during the seasons, while the oils of O. selloi did not. Methylchavicol and linalool were the main chemical components found in the aerial parts and leaves of O. canum. This finding permitted to characterize this specimen as a new chemotype of O. canum. Regarding the aerial parts of O. selloi, eugenol, 1,8-cineole, transcaryophyllene and linalool were identified as their major components. All extracted oils from the aerial parts showed biological activity against gram-positive cocci – Staphylococcus aureus ATCC 25923 – but only the O. canum one showed activity against gram-negative bacilli – Escherichia coli ATCC 25922.
这项研究描述了均生长于巴西东北部热基耶/巴伊亚州的卡努姆罗勒（Ocimum canum）和塞洛依罗勒（Ocimum selloi）挥发油的化学成分及抗菌活性。这些植物于2005年冬季和2006年夏季采集，通过水蒸气蒸馏法提取挥发油，并进一步用气相色谱-质谱联用仪（GC-MS）进行分析。分别从塞洛依罗勒和卡努姆罗勒的挥发油中鉴定出了30种和31种化合物。观察发现，卡努姆罗勒的含油量在不同季节有所变化，而塞洛依罗勒的挥发油则没有。甲基丁香酚和芳樟醇是在卡努姆罗勒地上部分和叶片中发现的主要化学成分。这一发现使得该样本被鉴定为卡努姆罗勒的一种新化学型。关于塞洛依罗勒的地上部分，丁香酚、1,8-桉叶素、反式石竹烯和芳樟醇被鉴定为其主要成分。从地上部分提取的所有挥发油均对革兰氏阳性球菌——金黄色葡萄球菌ATCC 25923——具有生物活性，但只有卡努姆罗勒的挥发油对革兰氏阴性杆菌——大肠杆菌ATCC 25922——具有活性。
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