Zenda Takahiro, Miyamoto Masaji, Kaneko Shuichi
Department of Internal Medicine, Tsurugi Municipal Hospital, Hakusan, Ishikawa, Japan.
Hiroshima J Med Sci. 2011 Jun;60(2):41-3.
A 56-year-old woman was admitted because of frequent watery diarrhea, vomiting, and abdominal cramps. An examination of the stool for norovirus antigen was positive, and a blood examination revealed a marked elevation of liver enzymes. Liver dysfunction, as well as symptoms related to gastroenteritis, was ameliorated solely by supportive treatment. Although liver injury concurrent with norovirus gastroenteritis is rarely documented and its pathogenesis remains unknown, clinicians should consider liver injury as one of the possible extra-intestinal manifestations of norovirus gastroenteritis.
一名56岁女性因频繁水样腹泻、呕吐和腹部绞痛入院。粪便诺如病毒抗原检测呈阳性，血液检查显示肝酶显著升高。肝功能障碍以及与肠胃炎相关的症状仅通过支持性治疗得到改善。虽然诺如病毒肠胃炎并发肝损伤鲜有记录且其发病机制尚不清楚，但临床医生应将肝损伤视为诺如病毒肠胃炎可能的肠外表现之一。
