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与儿童期性虐待相关的神经发育生物学

Neurodevelopmental biology associated with childhood sexual abuse.

作者信息

De Bellis Michael D, Spratt Eve G, Hooper Stephen R

机构信息

Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA.

出版信息

J Child Sex Abus. 2011 Sep;20(5):548-87. doi: 10.1080/10538712.2011.607753.

DOI:10.1080/10538712.2011.607753
PMID:21970646
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3769180/
Abstract

Child maltreatment appears to be the single most preventable cause of mental illness and behavioral dysfunction in the United States. Few published studies examine the developmental and the psychobiological consequences of sexual abuse. There are multiple mechanisms through which sexual abuse can cause post-traumatic stress disorder, activate biological stress response systems, and contribute to adverse brain development. This article will critically review the psychiatric problems associated with maltreatment and the emerging biologic stress system research with a special emphasis on what is known about victimization by sexual abuse.

摘要

在美国,儿童虐待似乎是精神疾病和行为功能障碍最可预防的单一原因。很少有已发表的研究探讨性虐待的发育和心理生物学后果。性虐待可通过多种机制导致创伤后应激障碍、激活生物应激反应系统并导致不良的大脑发育。本文将批判性地回顾与虐待相关的精神问题以及新兴的生物应激系统研究,特别强调关于性虐待受害者的已知情况。

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