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氟银双离子注入表面改性丙烯酸牙科器械的抗菌效果。

Antibacterial effect of acrylic dental devices after surface modification by fluorine and silver dual-ion implantation.

机构信息

Department of Pediatric Dentistry, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto, Tokushima 770-8504, Japan.

出版信息

Acta Biomater. 2012 Mar;8(3):1388-93. doi: 10.1016/j.actbio.2011.09.017. Epub 2011 Sep 22.

Abstract

The purpose of the present study was to examine the effectiveness of fluorine and silver ions implanted and deposited into acrylic resin (poly(methyl methacrylate)) using a hybrid process of plasma-based ion implantation and deposition. The surface characteristics were evaluated by X-ray photoelectron spectroscopy (XPS), contact angle measurements, and atomic force microscopy. In addition, an antibacterial activity test was performed by the adenosine-5'-triphosphate luminescence method. XPS spectra of modified specimens revealed peaks due to fluoride and silver. The water contact angle increased significantly due to implantation and deposition of both fluorine and silver ions. In addition, the presence of fluorine and silver was found to inhibit bacterial growth. These results suggest that fluorine and silver dual-ion implantation and deposition can provide antibacterial properties to acrylic medical and dental devices.

摘要

本研究旨在探讨利用等离子体基离子注入和沉积的混合工艺,将氟离子和银离子注入并沉积到丙烯酸树脂(聚甲基丙烯酸甲酯)中的效果。通过 X 射线光电子能谱(XPS)、接触角测量和原子力显微镜评估表面特性。此外,通过三磷酸腺苷发光法进行抗菌活性测试。改性样品的 XPS 光谱显示出氟和银的峰。由于氟和银离子的注入和沉积,水接触角显著增加。此外,发现氟和银的存在可以抑制细菌生长。这些结果表明,氟和银双离子注入和沉积可以为丙烯酸酯医疗和牙科器械提供抗菌性能。

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