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用于调节微生物生物膜的表面改性——在牙科医学中的应用

Surface Modification to Modulate Microbial Biofilms-Applications in Dental Medicine.

作者信息

Holban Alina-Maria, Farcasiu Catalina, Andrei Oana-Cella, Grumezescu Alexandru Mihai, Farcasiu Alexandru-Titus

机构信息

Microbiology & Immunology Department, Faculty of Biology, University of Bucharest, 77206 Bucharest, Romania.

Research Institute of the University of Bucharest-ICUB, University of Bucharest, 050657 Bucharest, Romania.

出版信息

Materials (Basel). 2021 Nov 18;14(22):6994. doi: 10.3390/ma14226994.

Abstract

Recent progress in materials science and nanotechnology has led to the development of advanced materials with multifunctional properties. Dental medicine has benefited from the design of such materials and coatings in providing patients with tailored implants and improved materials for restorative and functional use. Such materials and coatings allow for better acceptance by the host body, promote successful implantation and determine a reduced inflammatory response after contact with the materials. Since numerous dental pathologies are influenced by the presence and activity of some pathogenic microorganisms, novel materials are needed to overcome this challenge as well. This paper aimed to reveal and discuss the most recent and innovative progress made in the field of materials surface modification in terms of microbial attachment inhibition and biofilm formation, with a direct impact on dental medicine.

摘要

材料科学和纳米技术的最新进展已促成了具有多功能特性的先进材料的开发。牙科医学受益于此类材料和涂层的设计,为患者提供了定制的植入物以及用于修复和功能性用途的改良材料。此类材料和涂层能被宿主更好地接受,促进植入成功,并在与材料接触后减少炎症反应。由于许多牙科疾病受某些致病微生物的存在和活性影响,因此也需要新型材料来应对这一挑战。本文旨在揭示并讨论材料表面改性领域在抑制微生物附着和生物膜形成方面取得的最新创新性进展,这对牙科医学有直接影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f67/8625127/3279b179c821/materials-14-06994-g001.jpg

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