Martins Marcelino, Maia Filho Antonio L M, Costa Charllyton L S, Coelho Nayana P M F, Costa Maricilia S, Carvalho Regiane A
Collegiate of Physical Therapy, Faculdade Integral Diferencial, Teresina, PI, Brasil.
Rev Bras Fisioter. 2011 Aug-Sep;15(4):297-302.
Studies have demonstrated the beneficial effects of topical application of fatty acids as healing agents. The lipid fraction of Ovis aries have an anti-inflammatory action that accelerates the healing process. Ultrasound increases blood flow and the extensibility of collagen structures and tendons.
To assess the anti-inflammatory action of the Ovis aries lipid fraction associated to pulsed therapeutic ultrasound and friction in an induced tendinitis model.
Fifty Wistar rats were divided into four groups: control that consisted of Ovis aries gel for topical use; pulsed ultrasound plus oil free sterile lotion; pulsed ultrasound plus Ovis aries gel; and oil free sterile lotion for topical use alone. To induce tendinitis a 10 µL intratendinous injection of collagenase was injected into the right Achilles tendon of rats. Treatment consisted of daily applications of ultrasound using the following parameters: 10% pulsed mode, 10% pulsed frequency of 1 MHz and intensity of 0.5 W/cm² for seven or fourteen days.
After 7 days of treatment, only the Ovis aries plus ultrasound group showed statistically significant difference when compared to the control group.The variation in the number of inflammatory cells on animals treated for fourteen days for the control, ultrasound plus oil free, ultrasound plus Ovis aries, Ovis aries plus massage and massage plus oil free groups were statistically significant different, p<0.01. It was observed in animals treated for seven days that the ultrasound plus Ovis aries group was statistically significant better than the control group, p<0.05.
It can be concluded that treatment using ultrasound plus Ovis aries is more effective than other treatments as it produces significantly better reduction on the number of inflammatory cells at 7 and 14 days.
研究表明，局部应用脂肪酸作为愈合剂具有有益效果。绵羊的脂质部分具有抗炎作用，可加速愈合过程。超声可增加血流量以及胶原蛋白结构和肌腱的伸展性。
在诱导性肌腱炎模型中，评估与脉冲治疗超声和摩擦相关的绵羊脂质部分的抗炎作用。
50只Wistar大鼠分为四组：对照组，使用局部用绵羊凝胶；脉冲超声加无油无菌洗剂；脉冲超声加绵羊凝胶；以及单独局部使用无油无菌洗剂。为诱导肌腱炎，将10μL胶原酶经皮内注射到大鼠右跟腱中。治疗包括每天使用超声，参数如下：10%脉冲模式，1MHz的10%脉冲频率和0.5W/cm²的强度，持续7天或14天。
治疗7天后，与对照组相比，仅绵羊加超声组显示出统计学上的显著差异。对照组、超声加无油组、超声加绵羊组、绵羊加按摩组和按摩加无油组在治疗14天的动物中炎症细胞数量的变化具有统计学上的显著差异，p<0.01。在治疗7天的动物中观察到，超声加绵羊组在统计学上显著优于对照组，p<0.05。
可以得出结论，超声加绵羊的治疗方法比其他治疗方法更有效，因为它在7天和14天时能显著减少炎症细胞数量。
