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针刺联合红外线照射与西药治疗急性痛风性关节炎的疗效对比观察

[Comparative observation of the efficacy on acute gouty arthritis between acupuncture combined with infrared irradiation and western medicine].

作者信息

Zhou Lei, Xu Qun-Fei, Zhang Wu-Si

机构信息

Acupuncture-Moxibustion Department, Jinhua Municipal Hospital of TCM, Jinhua 321017, Zhejiang Province, China.

出版信息

Zhongguo Zhen Jiu. 2011 Sep;31(9):787-9.

Abstract

OBJECTIVE

To compare the efficacy difference in treatment of acute gouty arthritis between acupuncture combined with infrared irradiation and Indomethachin as well as observe the impacts on liver function.

METHODS

One hundred and sixty cases of gout were randomized into an acupuncture group (80 cases) and an Indomethachin group (80 cases). In acupuncture group, acupuncture was applied to Zusanli (ST 36), Sanyinjiao (SP 6), Quchi (LI 11), Xuehai (SP 10), Yanglingquan (GB 34) and Ashi points. Additionally, infrared irradiation was used in the local area. The treatment was given once daily. In Indomethachin group, Indomethachin was taken orally, 25 mg each time, three times per day. The treatment lasted for 5 days in either group. Separately, before and after treatment, pain severity and the levels of blood uric acid (BUA), erythrocyte sedimentation rate (ESR), alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were detected. Additionally, the efficacy and the impacts on liver function were assessed.

RESULTS

The curative rate was 52.5% (42/80) in acupuncture group, which was superior to 22.5% (18/80) in Indomethachin group (P < 0.01). In acupuncture group, the analgesia efficacy was better than that in Indomethachin group (P < 0.01) and the effect on reducing BUA and ERS levels was same as that in Indomethachin group (all P > 0.05). After treatment, ALT and AST levels had no changes in acupuncture group, but they increased apparently in Indomethachin group (all P < 0.01).

CONCLUSION

Acupuncture combined with infrared irradiation achieves superior efficacy on acute gouty arthritis as compared with oral medication of Indomethachin and the therapy provides a significant effect on analgesia and does not bring the damage of liver function.

摘要

目的

比较针刺联合红外线照射与吲哚美辛治疗急性痛风性关节炎的疗效差异,并观察其对肝功能的影响。

方法

将160例痛风患者随机分为针刺组(80例)和吲哚美辛组(80例)。针刺组选取足三里(ST 36)、三阴交(SP 6)、曲池(LI 11)、血海(SP 10)、阳陵泉(GB 34)及阿是穴进行针刺,并在局部进行红外线照射,每日治疗1次。吲哚美辛组口服吲哚美辛,每次25mg,每日3次。两组均治疗5天。分别于治疗前后检测疼痛程度、血尿酸(BUA)、红细胞沉降率(ESR)、丙氨酸氨基转移酶(ALT)及天冬氨酸氨基转移酶(AST)水平,并评估疗效及对肝功能的影响。

结果

针刺组治愈率为52.5%(42/80),优于吲哚美辛组的22.5%(18/80)(P<0.01)。针刺组镇痛效果优于吲哚美辛组(P<0.01),降低BUA及ERS水平的效果与吲哚美辛组相同(均P>0.05)。治疗后,针刺组ALT及AST水平无变化,而吲哚美辛组明显升高(均P<0.01)。

结论

与口服吲哚美辛相比,针刺联合红外线照射治疗急性痛风性关节炎疗效更佳,具有显著的镇痛作用,且不损害肝功能。

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