颅骨成形术距颅骨切除术的最短植入时间为6个月，以降低感染风险——82例患者的病例系列研究
The minimum time for cranioplasty insertion from craniectomy is six months to reduce risk of infection--a case series of 82 patients.
作者信息
Thavarajah Dushan, De Lacy Patricia, Hussien Ahmed, Sugar Adrian
机构信息
Department of Trauma and Orthopaedics, Whipps Cross University Hospital, Whipps Cross Road, Leytonstone, London.
出版信息
Br J Neurosurg. 2012 Feb;26(1):78-80. doi: 10.3109/02688697.2011.603850. Epub 2011 Oct 5.
OBJECTIVE
Cranioplasty is carried out for cosmesis, protection and also for neurological improvement following cranial defect. Infection post cranioplasty is problematic. We look at the outcome from 10 years of cranioplasty patients, and aim to see if there is a correlation between infection and time to insertion of cranial plate.
METHODS
A retrospective case series identifying all cranioplasty patients between 1998-2008 using the maxillofacial laboratory data log of all plates that were made during this time. Data was yielded from the clinical case notes and the microbiology database. The outcome measure was infection defined as removal of cranioplasty plate.
RESULTS
Total cranioplasties performed = 82. Infected cranioplasties = 9 (7 titanium 2 acrylic). An 11% infection rate of cranioplasties. Craniectomy due to trauma, with cranioplasty occurring between 0 to 6 months had the greatest number of infective cases, with 8 out of 9 occuring in this period (p value = 0.0076).
CONCLUSION
Cranioplasty carried out at a minimum of 6 months post craniectomy limits the risk of infection.
目的
颅骨成形术用于美容、保护以及改善颅骨缺损后的神经功能。颅骨成形术后感染是个问题。我们观察了10年颅骨成形术患者的结果，旨在探讨感染与颅骨板植入时间之间是否存在关联。
方法
一项回顾性病例系列研究，利用1998年至2008年期间制作的所有颅骨板的颌面实验室数据记录，确定所有颅骨成形术患者。数据来自临床病例记录和微生物学数据库。结局指标为感染，定义为取出颅骨成形板。
结果
共进行了82例颅骨成形术。感染的颅骨成形术有9例（7例钛板，2例丙烯酸板）。颅骨成形术的感染率为11%。因创伤行颅骨切除术，在0至6个月内行颅骨成形术的感染病例最多，9例中有8例发生在此期间（p值=0.0076）。
结论
颅骨切除术后至少6个月进行颅骨成形术可降低感染风险。
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