Al-Tamimi Yahia Z, Sinha Priyank, Trivedi Mili, Robson Craig, Al-Musawi Tamara A, Hossain Naveed, Mumford Christopher, Towns Gerry
Department of Neurosurgery, Leeds General Infirmary, Leeds, UK.
Br J Neurosurg. 2012 Aug;26(4):510-3. doi: 10.3109/02688697.2011.633640. Epub 2012 Jun 11.
There are many indications for cranioplasty with an increasing incidence partly attributable to an increase in decompressive craniectomy following trauma and stroke. The aim of this study was to compare the survival of acrylic and titanium cranioplasties used in our department.
Retrospective cohort study of 126 patients who underwent cranioplasty between 1997 and 2007. A comparison was made between those with acrylic (n = 61) and titanium (n = 65) cranioplasties. There was no significant difference in age and length of time between craniectomy and cranioplasty between the two groups. The indications for titanium cranioplasty tended to be classified as 'high risk' indications including trauma and stroke. A higher rate of pre-existing infection was noted in the acrylic group. Mean follow-up was 97.2 and 34 months for acrylic and titanium cranioplasties respectively.
Mean survival (95% confidence intervals) was 135 months (134-153) and 92 months (82-102) for acrylic and cranioplasty respectively. Out of 13 failures, only two were associated with pre-existing infection. Overall cumulative survival was better for acrylic cranioplasty although this difference did not reach statistical significance.
Although survival of acrylic cranioplasty appears to be better than titanium plates, there is no statistical significance. Acrylic has the advantage of being able to be applied at the time of surgery without any planning and does not cause artefact on future imaging. Titanium cranioplasty is strong, light-weight and inert and can be fashioned in the pre-operative setting.
颅骨修补术有多种适应证,其发病率不断上升,部分原因是创伤和中风后减压性颅骨切除术的增加。本研究的目的是比较我们科室使用的丙烯酸和钛质颅骨修补材料的存留情况。
对1997年至2007年间接受颅骨修补术的126例患者进行回顾性队列研究。对使用丙烯酸颅骨修补材料(n = 61)和钛质颅骨修补材料(n = 65)的患者进行比较。两组患者在年龄以及颅骨切除与颅骨修补之间的时间间隔方面无显著差异。钛质颅骨修补术的适应证往往被归类为“高风险”适应证,包括创伤和中风。丙烯酸组既往感染率较高。丙烯酸和钛质颅骨修补术的平均随访时间分别为97.2个月和34个月。
丙烯酸和钛质颅骨修补术的平均存留时间(95%置信区间)分别为135个月(134 - 153)和92个月(82 - 102)。在13例失败病例中,只有2例与既往感染有关。总体而言,丙烯酸颅骨修补术的累积存留情况更好,尽管这种差异未达到统计学意义。
尽管丙烯酸颅骨修补术的存留情况似乎优于钛板,但无统计学意义。丙烯酸材料的优点是能够在手术时直接应用而无需任何规划,并且不会在未来成像中产生伪影。钛质颅骨修补材料坚固、轻便且惰性强,可在术前塑形。