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老年护士职业性手部湿疹的二级预防的长期效果:一项对照研究设计的挑战。

Long-term effectiveness of secondary prevention in geriatric nurses with occupational hand eczema: the challenge of a controlled study design.

机构信息

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Sedanstrasse 115, 49090 Osnabrück, Germany.

出版信息

Contact Dermatitis. 2012 Feb;66(2):79-86. doi: 10.1111/j.1600-0536.2011.01976.x. Epub 2011 Oct 5.

DOI:10.1111/j.1600-0536.2011.01976.x
PMID:21974692
Abstract

BACKGROUND

The high prevalence of occupational dermatoses indicates the need for effective and sustainable prevention strategies.

OBJECTIVES

To evaluate the long-term effectiveness of secondary prevention in geriatric nurses.

PATIENTS/METHODS: One hundred and two geriatric nurses with occupational hand eczema participated in an interdisciplinary prevention programme [intervention group (IG)]. Members of the control group (CG) (n = 107) were medically treated by local dermatologists. Six years after intervention (T2), data on job continuation, skin lesions and skin protection behaviour were obtained by standardized questionnaires and compared with baseline values (T0) and data from a 3-month follow-up (T1).

RESULTS

At T2, 65.3% of the IG and 56.8% of the CG still worked as geriatric nurses; 6.9% of the IG and 13.6% of the CG had given up work because of occupational hand eczema. The skin status improved in both cohorts. The data indicated a lower frequency of skin lesions and morphological signs in the IG, for example vesicles (IG, 12.8%; CG, 40.0%; χ(2) = 7.00, degrees of freedom = 1, p = 0.008).

CONCLUSIONS

The results indicate long-term effects regarding job continuation and disease severity, although few results showed statistical significance. It is outlined that controlled long-term studies aiming at proving the general effectiveness of secondary prevention are no longer feasible in Germany, as the statutory accident insurance has led to a legal entitlement of all patients affected by occupational hand eczema to immediate preventive intervention.

摘要

背景

职业性皮肤病的高患病率表明需要采取有效的可持续预防策略。

目的

评估老年科护士二级预防的长期效果。

患者/方法:102 名患有职业性手部湿疹的老年科护士参加了一项跨学科预防计划(干预组[IG])。对照组(CG)(n=107)的成员由当地皮肤科医生进行药物治疗。干预 6 年后(T2),通过标准化问卷获得关于工作连续性、皮肤损伤和皮肤保护行为的数据,并与基线值(T0)和 3 个月随访(T1)的数据进行比较。

结果

在 T2,IG 中有 65.3%和 CG 中有 56.8%的人仍作为老年科护士工作;IG 中有 6.9%和 CG 中有 13.6%的人因职业性手部湿疹而放弃工作。两组的皮肤状况均有所改善。数据表明 IG 中皮肤损伤和形态学征象的频率较低,例如水疱(IG,12.8%;CG,40.0%;χ(2) = 7.00,自由度= 1,p = 0.008)。

结论

尽管有些结果具有统计学意义,但这些结果表明在工作连续性和疾病严重程度方面具有长期效果。需要指出的是,在德国,针对二级预防的一般有效性进行的受控长期研究已不再可行,因为法定事故保险已经使所有受职业性手部湿疹影响的患者有权立即获得预防性干预。

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