Department of Radiation Oncology, University of California Davis, Sacramento, CA 95817, USA.
Clin Nucl Med. 2011 Nov;36(11):e168-70. doi: 10.1097/RLU.0b013e318219b539.
Although the incidence of rib fractures after conventional radiotherapy is generally low (<2%), rib fractures are a relatively common complication of stereotactic body radiotherapy. For malignancy adjacent to the chest wall, the incidence of rib fractures after stereotactic body radiotherapy is as high as 10%. Unrecognized bone fractures can mimic bone metastases on bone scintigraphy, can lead to extensive workup, and can even lead to consideration of unnecessary systemic chemotherapy, as treatment decisions can be based on imaging findings alone. Nuclear medicine physicians and diagnostic radiologists should always consider rib fracture in the differential diagnosis.
虽然常规放射治疗后肋骨骨折的发生率通常较低(<2%),但肋骨骨折是立体定向体部放射治疗的一个相对常见的并发症。对于紧邻胸壁的恶性肿瘤,立体定向体部放射治疗后肋骨骨折的发生率高达 10%。未被识别的骨骨折可能在骨闪烁显像上模拟骨转移,可导致广泛的检查,甚至可能导致不必要的全身化疗的考虑,因为治疗决策可以仅基于影像学发现。核医学医师和诊断放射科医师应始终在鉴别诊断中考虑肋骨骨折。