The Mount Sinai School of Medicine, New York, NY 10029, USA.
J Atten Disord. 2012 Nov;16(8):631-4. doi: 10.1177/1087054711416910. Epub 2011 Oct 5.
To empirically identify the appropriate symptom threshold for hyperactivity-impulsivity for diagnosis of ADHD in adults.
Participants were 88 adults (M [SD] age = 41.69 [11.78] years, 66% female, 16% minority) meeting formal DSM-IV criteria for ADHD combined or predominantly inattentive subtypes based on a structured diagnostic interview keyed to DSM-IV (Conners' Adult ADHD Diagnostic Interview for DSM-IV [CAADID]). All participants also completed the Conners' Adult ADHD Rating Scale (CAARS), which was normed on the general adult population and includes subscales for DSM-IV inattentive and DSM-IV hyperactive-impulsive symptoms. A T-score threshold of 65 (at least 1.5 SD above population mean) on the CAARS DSM-IV hyperactive-impulsive dimension was used to identify participants with empirically elevated symptom severity.
Of 88 participating adults, 48 (55%) had a T-score of at least 65 (1.5 SD) on the CAARS DSM-IV Hyperactive-Impulsive scale. Of these, only 25 (52%) met the DSM-IV cutoff of six hyperactive-impulsive symptoms on the CAADID. Thus, approximately half of those who reported empirically elevated hyperactive-impulsive complaints on the CAARS did not concurrently meet the six-symptom DSM-IV cutoff on the CAADID. An alternative cutoff of four hyperactive-impulsive symptoms on the CAADID captured 39 (81%) cases identified by the CAARS.
In adults, mandating at least six hyperactive-impulsive symptoms excludes a significant percentage (almost half) of adults who are at least 1.5 SD above the population mean on a dimensional measure of hyperactivity-impulsivity. These data provide a compelling basis for lowering the symptom threshold of hyperactivity-impulsivity for adults in the DSM-5.
通过实证研究确定多动-冲动症状的恰当阈值,以便将其用于成人 ADHD 的诊断。
88 名符合 DSM-IV 诊断标准的成年 ADHD 患者(综合型或注意缺陷主导型)参加了此项研究。该研究采用了与 DSM-IV 相对应的结构化诊断访谈,即康纳斯成人 ADHD 诊断访谈-IV(CAADID)。所有参与者同时完成了康纳斯成人 ADHD 评定量表(CAARS)的测试,该量表以一般成年人群为参照,包含 DSM-IV 注意缺陷和 DSM-IV 多动-冲动症状的子量表。使用 CAARSDSM-IV 多动-冲动分量表的 T 分数阈值(至少比常模群体高出 1.5 个标准差)来确定症状严重程度达到实证标准的患者。
在 88 名参与研究的成年人中,有 48 名(55%)CAARSDSM-IV 多动-冲动分量表的 T 分数至少为 65(1.5 个标准差)。其中,只有 25 名(52%)符合 CAADID 上的 DSM-IV 六个多动-冲动症状的诊断标准。因此,大约一半在 CAARS 上报告了实证性的多动-冲动症状的患者,并没有同时符合 CAADID 上的 DSM-IV 六个症状的诊断标准。CAADID 上的四个多动-冲动症状的替代诊断标准可以捕捉到 CAARS 确定的 39 例(81%)病例。
在成年人中,至少六个多动-冲动症状的诊断标准将大多数(近一半)在多动-冲动维度上的得分至少比常模群体高出 1.5 个标准差的成年人排除在外。这些数据为降低 DSM-5 中成人多动-冲动症状的诊断标准提供了有力的依据。