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成人注意力缺陷多动障碍阳性筛查的功能损害:症状表现和执行功能的作用。

Functional impairment in adults positively screened for attention-deficit hyperactivity disorder: the role of symptom presentation and executive functioning.

机构信息

Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary.

出版信息

Compr Psychiatry. 2013 Oct;54(7):974-81. doi: 10.1016/j.comppsych.2013.04.002. Epub 2013 May 16.

DOI:10.1016/j.comppsych.2013.04.002
PMID:23684546
Abstract

BACKGROUND

While the number of symptoms of attention-deficit hyperactivity disorder (ADHD) decreases with age, a high proportion of adults with ADHD symptoms suffer from persistent functional impairment (Fi) linked to these symptoms. Our objective was to investigate the specific roles of two potentially important predictors of this Fi: the clinical symptom presentation and the deficit in executive functions (EFs).

METHODS

A total of 158 subjects from a community sample positively screened for ADHD were classified into two groups: those with and without Fi. Following a detailed diagnostic process, participants were administered a self-rating scale for ADHD symptoms as well as a neuropsychological test battery containing tests of EF and attention relevant as potential cognitive endophenotypes for ADHD.

RESULTS

The overall number as well as the number of inattentive, hyperactive and impulsive symptoms, confirmed both by examiner and self-report, were significantly higher among Fi subjects. The highest odds ratio for Fi was associated with impulsive symptoms. Additionally, self-reported complaints of problems with self-concept were significantly higher among Fi subjects. No significant relationship between Fi and neuropsychological measures of EF and attention was detected.

CONCLUSIONS

This study revealed that the number of symptoms, in particular that of impulsivity, had a significant impact on Fi in adults with symptoms of ADHD. Furthermore, our results underline the importance of assessing complaints and behaviors related to self-concept, which are not included in DSM-IV diagnostic criteria of ADHD but nonetheless may be associated with functional outcome of the disorder.

摘要

背景

尽管注意力缺陷多动障碍(ADHD)的症状数量会随着年龄的增长而减少,但仍有很大比例的 ADHD 症状成年人持续存在与这些症状相关的功能障碍(Fi)。我们的目的是研究两种可能对这种 Fi 具有重要预测作用的因素:临床症状表现和执行功能(EF)缺陷。

方法

从社区样本中筛选出 158 名 ADHD 阳性者,他们被分为有 Fi 和无 Fi 两组。在经过详细的诊断过程后,参与者接受了 ADHD 症状自评量表以及神经心理学测试,其中包含与 ADHD 相关的 EF 和注意力测试,这些测试可能是潜在的认知表型。

结果

Fi 组的总体症状数量以及注意力不集中、多动和冲动症状数量均明显高于无 Fi 组,无论是通过检查者评估还是自我报告都是如此。冲动症状与 Fi 的最高比值相关。此外,Fi 组自我报告的自我概念问题的抱怨明显更多。Fi 与 EF 和注意力的神经心理学测量之间没有显著关系。

结论

本研究表明,在有 ADHD 症状的成年人中,症状数量,特别是冲动症状数量,对 Fi 有显著影响。此外,我们的结果强调了评估与自我概念相关的抱怨和行为的重要性,这些抱怨和行为虽然不在 DSM-IV ADHD 诊断标准中,但可能与该疾病的功能结果有关。

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