肌钙蛋白T水平对风湿性心脏病的诊断有帮助吗？
Can troponin T levels be useful in the diagnosis of rheumatic carditis?
作者信息
Ertug Mehmet Halil, Yılmaz Gokben Gorsel, Akçurin Gayaz, Kardelen Fırat, Kocabas Abdullah, Gumuşlu Saadet, Genç Sibel Kuloglu
机构信息
Department of Pediatric Cardiology, Akdeniz University School of Medicine, Arapsuyu, Antalya, Turkey.
出版信息
Ann Pediatr Cardiol. 2011 Jul;4(2):156-8. doi: 10.4103/0974-2069.84657.
OBJECTIVE
Acute rheumatic fever (ARF) is an endemic disease observed in children of developing countries. The purpose of this study was to test if it was possible to identify myocardial involvement in cases with rheumatic carditis by the measurement of serum cardiac TnT.
METHODS
30 patients diagnosed as ARF underwent echocardiography and their cardiac troponin T (cTnT) serum levels were measured. Patients were divided into group 1: Arthritis alone, group 2: carditis, and group 3 carditis with congestive heart failure (CHF).
RESULTS
cTnT serum levels were normal in all except one patient with in group 3. Two patients in carditis (group 2) and three patients in CHF (group 3) had dilation in left ventricular end diastolic diameter.
CONCLUSIONS
Normal cTnT levels in our patient group suggests that inflammation rather than myocardial necrosis is predominant in ARF carditis.
目的
急性风湿热（ARF）是发展中国家儿童中观察到的一种地方病。本研究的目的是通过测量血清心肌肌钙蛋白T（cTnT）来检验是否有可能识别风湿性心脏炎病例中的心肌受累情况。
方法
30例诊断为ARF的患者接受了超声心动图检查，并测量了他们的心肌肌钙蛋白T（cTnT）血清水平。患者被分为1组：仅有关节炎；2组：心脏炎；3组：伴有充血性心力衰竭（CHF）的心脏炎。
结果
除3组中的1例患者外，所有患者的cTnT血清水平均正常。心脏炎组（2组）中的2例患者和CHF组（3组）中的3例患者左心室舒张末期内径增大。
结论
我们患者组中cTnT水平正常表明，在ARF心脏炎中炎症而非心肌坏死占主导地位。
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