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原发性阴道小细胞神经内分泌癌：一例罕见病例报告

Primary small cell neuroendocrine carcinoma of vagina: a rare case report.

作者信息

Bhalodia Jignasa N, Kapapura Dhiren V, Parekh Malay N

机构信息

Department of Pathology, GMERES Medical College Sola, B-37, Marutinandan Vihar Bungalows, Near Aarohi Villa, S.P. Ring Road, Bopal, Ahmedabad 380058, India.

出版信息

Patholog Res Int. 2011;2011:306921. doi: 10.4061/2011/306921. Epub 2011 Oct 3.

DOI:10.4061/2011/306921
PMID:21977334
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3185235/
Abstract

Primary small cell neuroendocrine carcinoma of vagina is an extremely rare disease. There have been only 26 previously reported cases in literature. Here, we report a case of primary small cell neuroendocrine carcinoma of vagina. Immunohistochemistry (IHC) showed tumor cells positive for synaptophysin, chromogranin, and neuron-specific enolase (NSE).

摘要

原发性阴道小细胞神经内分泌癌是一种极其罕见的疾病。文献中此前仅报道过26例病例。在此，我们报告一例原发性阴道小细胞神经内分泌癌。免疫组织化学（IHC）显示肿瘤细胞突触素、嗜铬粒蛋白和神经元特异性烯醇化酶（NSE）呈阳性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/834a/3185235/c51e1769e19a/PRI2011-306921.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/834a/3185235/ab91dd9335dc/PRI2011-306921.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/834a/3185235/948bd6b48684/PRI2011-306921.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/834a/3185235/6e6ad7dbecf8/PRI2011-306921.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/834a/3185235/7d77835c22a1/PRI2011-306921.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/834a/3185235/5836297ea739/PRI2011-306921.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/834a/3185235/c51e1769e19a/PRI2011-306921.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/834a/3185235/ab91dd9335dc/PRI2011-306921.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/834a/3185235/948bd6b48684/PRI2011-306921.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/834a/3185235/6e6ad7dbecf8/PRI2011-306921.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/834a/3185235/7d77835c22a1/PRI2011-306921.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/834a/3185235/5836297ea739/PRI2011-306921.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/834a/3185235/c51e1769e19a/PRI2011-306921.006.jpg

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Pol J Pathol. 2007;58(1):23-33.
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BMJ Case Rep. 2022 Oct 31;15(10):e252031. doi: 10.1136/bcr-2022-252031.
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Protein Expression Profiling and Virtual Drug Screening as an Approach for Individualized Therapy of Small Cell Vaginal Carcinoma.蛋白质表达谱分析和虚拟药物筛选作为小细胞阴道癌个体化治疗的一种方法。
Cancer Genomics Proteomics. 2022 Jul-Aug;19(4):512-525. doi: 10.21873/cgp.20337.
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Emerging Therapeutic Concepts and Latest Diagnostic Advancements Regarding Neuroendocrine Tumors of the Gynecologic Tract.妇科生殖道神经内分泌肿瘤的治疗新观念与最新诊断进展。
Medicina (Kaunas). 2021 Dec 7;57(12):1338. doi: 10.3390/medicina57121338.
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