Koutourousiou Maria, Snyderman Carl H, Fernandez-Miranda Juan, Gardner Paul A
Department of Neurological Surgery, University of Pittsburgh School of Medicine, 200 Lothrop Street, PUH 400, Pittsburgh, PA 15213, USA.
Otolaryngol Clin North Am. 2011 Oct;44(5):1155-71. doi: 10.1016/j.otc.2011.06.002. Epub 2011 Jul 21.
Skull base chordomas are rare midline malignancies of clival origin that represent one of the most challenging skull base tumors to treat, given their location, invasiveness, potential extension around vital neurovascular structures, and high recurrence rate. Total tumor resection is the mainstay of treatment. The combination of surgery and postoperative irradiation appears to provide the best outcome.
颅底脊索瘤是起源于斜坡的罕见中线恶性肿瘤，鉴于其位置、侵袭性、在重要神经血管结构周围的潜在扩展以及高复发率，它是最难治疗的颅底肿瘤之一。肿瘤全切是主要的治疗方法。手术与术后放疗相结合似乎能提供最佳疗效。
