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建立多中心临床研究网络:经验教训。

Establishing a multicentre clinical research network: lessons learned.

机构信息

Tom Baker Cancer Centre, Alberta Health Services Cancer Care, Calgary, AB.

出版信息

Curr Oncol. 2011 Oct;18(5):e243-9. doi: 10.3747/co.v18i5.814.

Abstract

BACKGROUND

Within many health care disciplines, research networks have emerged to connect researchers who are physically separated, to facilitate sharing of expertise and resources, and to exchange valuable skills. A multicentre research network committed to studying difficult cancer pain problems was launched in 2004 as part of a Canadian initiative to increase palliative and end-of-life care research capacity. Funding was received for 5 years to support network activities.

METHODS

Mid-way through the 5-year granting period, an external review panel provided a formal mid-grant evaluation. Concurrently, an internal evaluation of the network by survey of its members was conducted. Based on feedback from both evaluations and on a review of the literature, we identified several components believed to be relevant to the development of a successful clinical cancer research network.

RESULTS

THESE COMMON ELEMENTS OF SUCCESSFUL CLINICAL CANCER RESEARCH NETWORKS WERE IDENTIFIED: shared vision, formal governance policies and terms of reference, infrastructure support, regular and effective communication, an accountability framework, a succession planning strategy to address membership change over time, multiple strategies to engage network members, regular review of goals and timelines, and a balance between structure and creativity.

CONCLUSIONS

In establishing and conducting a multi-year, multicentre clinical cancer research network, network members were led to reflect on the factors that contributed most to the achievement of network goals. Several specific factors were identified that seemed to be highly relevant in promoting success. These observations are presented to foster further discussion on the successful design and operation of research networks.

摘要

背景

在许多医疗保健学科中,已经出现了研究网络,将物理上分离的研究人员联系在一起,以促进专业知识和资源的共享,并交流有价值的技能。一个致力于研究癌症疼痛难题的多中心研究网络于 2004 年成立,作为加拿大提高姑息治疗和临终关怀研究能力倡议的一部分。该网络获得了为期 5 年的资金支持,以支持网络活动。

方法

在 5 年拨款期的中途,外部评审小组提供了正式的中期拨款评估。同时,对网络成员进行了内部评估。根据这两个评估以及对文献的回顾,我们确定了几个被认为与成功开展临床癌症研究网络相关的组成部分。

结果

这些成功的临床癌症研究网络的共同要素包括:共同愿景、正式的治理政策和职权范围、基础设施支持、定期有效的沟通、问责制框架、解决成员随时间变化的继任规划策略、多种吸引网络成员的策略、定期审查目标和时间表,以及结构和创造力之间的平衡。

结论

在建立和开展多年的多中心临床癌症研究网络时,网络成员被引导思考对实现网络目标贡献最大的因素。确定了几个似乎对促进成功非常重要的具体因素。这些观察结果旨在促进对研究网络的成功设计和运作的进一步讨论。

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