Willson Douglas F, Dean J Michael, Newth Christopher, Pollack Murray, Anand K J S, Meert Kathleen, Carcillo Joseph, Zimmerman Jerry, Nicholson Carol
University of Virginia Children's Hospital, USA.
Pediatr Crit Care Med. 2006 Jul;7(4):301-7. doi: 10.1097/01.PCC.0000227106.66902.4F.
Pediatric critical care was formally recognized as a separate subspecialty in pediatrics in 1987. Since that time the numbers of pediatric intensivists, pediatric intensive care units, and pediatric intensive care beds in the United States have increased dramatically. Research efforts have lagged behind, however, as this new discipline has struggled to identify the necessary time, funding, and other resources to pursue clinical and laboratory investigation. In April 2004, the National Center for Medical Rehabilitation Research of the National Institute for Child Health and Human Development issued a request for applications to establish the Collaborative Pediatric Critical Care Research Network (CPCCRN). The CPCCRN provides an infrastructure to pursue collaborative clinical trials and descriptive studies in pediatric critical care medicine. Six pediatric centers involving seven intensive care units and a data-coordinating center were identified through a competitive application process. Network goals include the support of collaborative clinical trials otherwise impracticable in single institutions and the establishment of a framework for developing the scientific basis for pediatric critical care practice. This article describes how the CPCCRN was established, its organization, and its goals and future plans.
1987年，儿科重症监护被正式承认为儿科学中的一个独立亚专业。自那时起，美国儿科重症医学专家的数量、儿科重症监护病房的数量以及儿科重症监护病床的数量都急剧增加。然而，由于这一新学科一直在努力确定开展临床和实验室研究所需的时间、资金及其他资源，研究工作一直滞后。2004年4月，国家儿童健康与人类发展研究所的国家医学康复研究中心发布了一份申请邀请，以建立协作性儿科重症监护研究网络（CPCCRN）。CPCCRN提供了一个基础设施，用于开展儿科重症监护医学方面的协作性临床试验和描述性研究。通过竞争性申请程序，确定了六个涉及七个重症监护病房的儿科中心和一个数据协调中心。网络目标包括支持在单个机构中难以开展的协作性临床试验，以及建立一个框架，为儿科重症监护实践奠定科学基础。本文介绍了CPCCRN是如何建立的、其组织架构、目标以及未来计划。
