National Marrow Donor Program (NMDP) and Center for International Blood and Marrow Transplant Research (CIBMTR), Minneapolis, Minnesota 55413, USA.
Transfusion. 2012 Apr;52(4):787-93. doi: 10.1111/j.1537-2995.2011.03383.x. Epub 2011 Oct 7.
This study measured: 1) levels of awareness and understanding among practicing obstetricians regarding umbilical cord blood (UCB) donation and the use of UCB in transplant therapy, 2) motivations for obstetricians to support donation and collection for donation to a public cord blood bank (CBB), and 3) current practices for discussing this option with their patients.
Obstetricians practicing in major metropolitan areas in the United States were randomly surveyed in 2009. Of 2041 surveys mailed, 295 were returned, 139 from obstetricians with privileges at hospitals affiliated with a public CBB (affiliated) and 156 from obstetricians without such privileges (nonaffiliated). Cross-tabulation analyses were conducted to compare responses between these two groups.
Both affiliated and nonaffiliated obstetricians report being somewhat or very familiar with the use of cord blood in transplant therapy (88% vs. 82%, respectively; p = NS), but some misperceptions concerning clinical application exist. Eighty percent of affiliated obstetricians feel confident discussing cord blood options with their patients; however, 49% indicated that they have insufficient knowledge of cord blood donation to effectively answer patients' questions about donation.
Obstetricians are generally familiar with the utility of donated cord blood in transplantation, but could benefit from additional information regarding how cord blood is used in transplantation. Further, obstetricians play an important role in encouraging women to donate their baby's cord blood to a public CBB, are willing to do so, and indicate a desire for more information so they can effectively educate their patients.
本研究旨在:1)评估实施剖宫产的妇产科医生对脐带血(UCB)捐献及 UCB 在移植治疗中应用的认知和了解程度;2)了解妇产科医生支持捐献并将脐带血捐献给公共脐带血库(CBB)的动机;3)探讨目前与患者讨论该选择的实际情况。
2009 年,我们以美国主要大都市地区的执业妇产科医生为研究对象,进行了随机调查。在邮寄的 2041 份调查问卷中,共回收 295 份,其中 139 份来自在与公共 CBB 有合作关系的医院执业的妇产科医生(关联组),156 份来自无合作关系的妇产科医生(非关联组)。我们对这两组的回答进行了交叉表分析。
关联组和非关联组的妇产科医生均报告称对脐带血在移植治疗中的应用较为熟悉(分别为 88%和 82%,p=NS),但对临床应用存在一些误解。80%的关联组妇产科医生认为自己有信心与患者讨论脐带血选择问题,但有 49%的医生表示,他们对脐带血捐献的知识了解不足,无法有效解答患者关于捐献的问题。
妇产科医生通常熟悉捐献脐带血在移植中的应用,但他们可能需要更多关于脐带血在移植中应用的信息。此外,妇产科医生在鼓励产妇将婴儿的脐带血捐献给公共 CBB 方面发挥着重要作用,他们愿意这样做,并表示希望获得更多信息,以便能够有效地教育患者。