Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Vet J. 2011 Oct;190(1):124-30. doi: 10.1016/j.tvjl.2010.09.011.
Sixty dairy herds were studied to investigate the association between long-term incidence of displaced abomasum and clinical ketosis and body condition score and blood profiles, including parameters estimating energy metabolism and hepatic lipidosis in the periparturient period and early lactation. Blood samples were taken around parturition and in early lactation from cows without apparent clinical symptoms of metabolic disorders. A difference in metabolism between high and low incidence herds was shown post-partum by a lower metabolic index (the revised Quantitative Insulin Sensitivity Check Index, RQUICKI), and tendencies for higher concentrations of glucose, insulin and non-esterified fatty acids in the high incidence herds. High incidence herds had more cows and produced on average 1400kg energy-corrected milk per cow per year more than the low incidence herds. No differences were found in parameters reflecting liver cell damage. In the first 3weeks post-partum the RQUICKI was a more sensitive marker of herds with a high incidence of displaced abomasum and clinical ketosis than any of the individual parameters, but further research is needed before practical applications of the RQUICKI can be foreseen.
对 60 个奶牛场进行了研究,以调查围产期和泌乳早期能量代谢和肝脂肪变性的参数估计,长期发生的真胃移位与临床酮病和体况评分以及血液特征之间的关系。从没有明显代谢紊乱临床症状的奶牛在分娩前后和泌乳早期采集血液样本。产后,高发病率和低发病率牛群之间的代谢差异表现为较低的代谢指数(改良定量胰岛素敏感性检查指数,RQUICKI),以及高发病率牛群中葡萄糖、胰岛素和非酯化脂肪酸浓度升高的趋势。高发病率牛群的奶牛数量更多,平均每年每头奶牛生产的能量校正奶量比低发病率牛群多 1400kg。反映肝细胞损伤的参数没有差异。产后 3 周内,RQUICKI 是发生真胃移位和临床酮病的高发病率牛群的更敏感标志物,比任何单个参数都敏感,但在预见 RQUICKI 的实际应用之前,还需要进一步的研究。