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英格兰国家初级保健指南:对南亚人群慢性肾脏病预防的影响。

National primary care guidelines for England: impact on chronic kidney disease prevention in South Asian populations.

机构信息

University of Bedfordshire, Luton, UK.

出版信息

J Nephrol. 2012 Sep-Oct;25(5):661-71. doi: 10.5301/jn.5000037.

Abstract

INTRODUCTION

This study evaluated the impact of national policy for kidney disease in primary care comparing South Asian (SA) and white European (WE) population groups.

METHODS

Retrospective audits of primary care records of SA and WE adults diagnosed with diabetes in 2004 and 2007 were carried out in a total sample of 707 patients across 18 general practices within Luton, Leicester and West London.

RESULTS

Four hundred patients (SA: n=241, and WE: n=159) were diagnosed as diabetic in 2004, and 307 (SA: n=178, and WE: n=129) in 2007. South Asian patients were 9-10 years younger, had lower systolic blood pressure than white Europeans at diagnosis in both years (136.1 vs. 141.4 mm Hg, p=0.01, in 2004; and 134 vs. 142.3 mm Hg, p=0.000, in 2007) and significantly higher HbA1c (8.6%, 63 mmol/L vs. 7.9%, 71 mmol/L) at diagnosis in 2004 than in 2007 (8.3%, 67 mmol/L vs. 8.2%, 66 mmol/L). Recording of the majority of variables associated with diabetic kidney disease increased across both patient groups between 2004 and 2007: albumin to creatinine ratio (up 13.0% in SA to 37.9%, and 15.1% in WE to 40.3%), estimated glomerular filtration rate (up 61.7% in SA to 70.8% and 75.6% in WE to 80.6%) and proteinuria (up 19.3% in SA to 46.3% and 26.1% in WE to 51.9%).

CONCLUSIONS

Recording of indicators for diabetic kidney disease at diagnosis increased in both South Asians and white Europeans following introduction of national guidance to improve early detection and quality of care in the diabetic kidney disease care pathway.

摘要

简介

本研究评估了国家肾脏疾病政策对初级保健的影响,比较了南亚(SA)和白种欧洲(WE)人群。

方法

对 2004 年和 2007 年在卢顿、莱斯特和伦敦西部的 18 家全科诊所共 707 名确诊为糖尿病的 SA 和 WE 成年患者的全科记录进行了回顾性审计。

结果

2004 年有 400 名患者(SA:n=241,WE:n=159)被诊断为糖尿病,2007 年有 307 名患者(SA:n=178,WE:n=129)。SA 患者比 WE 患者年轻 9-10 岁,在这两年的诊断中,SA 患者的收缩压低于 WE 患者(2004 年:136.1 对 141.4mmHg,p=0.01;2007 年:134 对 142.3mmHg,p=0.000),且 2004 年的 HbA1c(8.6%,63mmol/L)明显高于 2007 年(8.3%,67mmol/L)。2004 年至 2007 年间,两组患者中与糖尿病肾病相关的大多数变量的记录均有所增加:白蛋白与肌酐比值(SA 增加 13.0%,达到 37.9%,WE 增加 15.1%,达到 40.3%)、估计肾小球滤过率(SA 增加 61.7%,达到 70.8%,WE 增加 75.6%,达到 80.6%)和蛋白尿(SA 增加 19.3%,达到 46.3%,WE 增加 26.1%,达到 51.9%)。

结论

在国家指南出台后,旨在改善糖尿病肾病患者的早期发现和护理质量,提高了 SA 和 WE 患者的诊断时糖尿病肾病指标的记录。

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