Diabetes and Transcription Factors, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW, 2010, Australia.
Arch Immunol Ther Exp (Warsz). 2011 Dec;59(6):421-9. doi: 10.1007/s00005-011-0143-0. Epub 2011 Oct 8.
Islet transplantation has the potential to cure type 1 diabetes. In recent years, the proportion of patients achieving initial insulin independence has improved, but longer term outcomes remain poor compared to those for whole pancreas transplants. This review article will discuss factors affecting islet yield and viability leading up to transplantation and in the immediate post-transplant period.
胰岛移植有可能治愈 1 型糖尿病。近年来,实现初始胰岛素独立性的患者比例有所提高,但与整个胰腺移植相比,长期结果仍较差。本文综述将讨论影响胰岛产量和活力的因素,这些因素涉及移植前和移植后即刻的阶段。