University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian, Scotland.
J Vet Intern Med. 2011 Sep-Oct;25(5):1186-9. doi: 10.1111/j.1939-1676.2011.00779.x. Epub 2011 Aug 30.
In South Africa, canine babesiosis typically is an acute disease in susceptible individuals and is a major cause of morbidity and mortality. Despite the importance of the disease, there have been no large studies that have examined the influence of breed and sex on disease susceptibility.
Toy breeds have a lower risk of babesiosis than working dogs.
A total of 1,222 dogs diagnosed with canine babesiosis and 11,484 noninfected dogs presented to the Onderstepoort Veterinary Academic Hospital's small animal outpatient clinic between 2004 and 2010.
Retrospective study.
Intact male, neutered male, and neutered female dogs had a significantly higher odds of being diagnosed with canine babesiosis compared to intact female dogs. Five of the 6 Toy breeds had significantly lower odds of being diagnosed with canine babesiosis than did the reference breed, Labrador Retrievers. In contrast, none of the 8 working dog breeds had significantly lower odds compared to the reference breed.
Intact male, neutered male, and neutered female dogs were at increased risk of canine babesiosis compared to intact female dogs. Several dog breeds, notably Toy breeds, had a lower risk of babesiosis in a hospital population of dogs in South Africa. The mechanism or mechanisms by which Toy breeds are protected from developing canine babesiosis may be related to genetic background or environmental exposure and deserves further study.
在南非，犬巴贝斯虫病通常是易感个体的急性疾病，是发病率和死亡率的主要原因。尽管这种疾病很重要，但还没有大规模的研究来检查品种和性别对疾病易感性的影响。
玩具品种患巴贝斯虫病的风险低于工作犬。
2004 年至 2010 年间，共有 1222 只被诊断患有犬巴贝斯虫病的狗和 11484 只未感染的狗在奥登斯堡兽医学术医院的小动物门诊就诊。
回顾性研究。
未绝育雄性、绝育雄性和绝育雌性犬患犬巴贝斯虫病的几率明显高于未绝育雌性犬。在 6 种玩具品种中，有 5 种患犬巴贝斯虫病的几率明显低于参考品种拉布拉多猎犬。相比之下，8 种工作犬种中没有一种与参考品种相比患犬巴贝斯虫病的几率明显降低。
与未绝育的雌性犬相比，未绝育的雄性、绝育的雄性和绝育的雌性犬患犬巴贝斯虫病的风险增加。在南非的一个犬科医院人群中，一些犬种，特别是玩具品种，患巴贝斯虫病的风险较低。玩具品种免受犬巴贝斯虫病侵害的机制可能与遗传背景或环境暴露有关，值得进一步研究。
