Puri Rajesh, Sud Randhir, Khaliq Abdul, Kumar Mandhir, Jain Sanjay
Department of Gastroenterology, Medanta, the Medicity, Gurgaon, India.
Indian J Gastroenterol. 2011 Sep;30(5):233-6. doi: 10.1007/s12664-011-0110-z. Epub 2011 Oct 11.
Traditional medicine is widely practiced in tropical countries. Bottle gourd (Lagenaria siceraria) fruit juice is advocated as a part of complementary and alternative medicine. If the bottle gourd juice becomes bitter it is considered toxic. We report 15 patients, who developed toxicity due to drinking bitter bottle gourd juice. Patients presented with abdominal pain, vomiting, hematemesis, diarrhea and hypotension within 15 min to 6-h after ingestion of bottle gourd juice. Endoscopy showed esophagitis, gastric erosions, ulcers and duodenitis. Hypotension was treated with crystalloids and inotropic support. All patients recovered in 1-4 days. Endoscopically the lesions healed in 2 weeks. Bitter bottle gourd can cause gastrointestinal toxicity with hematemesis and hypotension. Supportive management is the treatment and all patients recover within 1 week.
传统医学在热带国家广泛应用。葫芦（葫芦科葫芦属）果汁被提倡作为补充和替代医学的一部分。如果葫芦汁变苦，则被认为有毒。我们报告了15例因饮用苦葫芦汁而出现中毒的患者。患者在摄入葫芦汁后15分钟至6小时内出现腹痛、呕吐、呕血、腹泻和低血压。内镜检查显示食管炎、胃糜烂、溃疡和十二指肠炎症。低血压通过晶体液和血管活性药物支持治疗。所有患者在1至4天内康复。内镜检查显示病变在2周内愈合。苦葫芦可导致伴有呕血和低血压的胃肠道中毒。支持性治疗是主要治疗方法，所有患者在1周内康复。
