Lestre Sara Isabel Alcântara, Gameiro Catarina Diogo, João Alexandre, Lopes Maria João Paiva
Serviço de Dermatologia, Hospital Santo António dos Capuchos, Lisboa, Portugal.
An Bras Dermatol. 2011 Jul-Aug;86(4):759-62. doi: 10.1590/s0365-05962011000400021.
Immunotherapy with Bacillus Calmette-Guérin is widely used for treatment and prophylaxis of superficial urothelial cancer. Complications associated with Bacillus Calmette-Guérin treatment are common. The authors describe a case of granulomatous inflammation of the penis associated with intravesical Bacillus Calmette-Guérin therapy, presenting with multiple erythematous and painless nodules located on the glans. A review of the literature is also performed. Granulomatous balanoposthitis is a rare complication of Bacillus Calmette-Guérin immunotherapy, with heterogeneous clinical presentation, which can make the diagnosis difficult. Its clinical recognition is essential for early start of therapy with antitubercular agents and interruption of Bacillus Calmette-Guérin.
卡介苗免疫疗法广泛用于浅表性尿路上皮癌的治疗和预防。卡介苗治疗相关的并发症很常见。作者描述了一例与膀胱内卡介苗治疗相关的阴茎肉芽肿性炎症病例，表现为龟头出现多个红斑且无痛性结节。同时还进行了文献综述。肉芽肿性阴茎头炎是卡介苗免疫疗法的一种罕见并发症，临床表现多样，可能导致诊断困难。其临床识别对于早期开始抗结核药物治疗和停用卡介苗至关重要。
