Shandong Medical Imaging Research Institute, Shandong University, 324 Jingwu Road, Jinan, China.
Eur Radiol. 2012 Feb;22(2):404-10. doi: 10.1007/s00330-011-2270-8. Epub 2011 Oct 11.
To evaluate the efficacy and safety of MRI-guided percutaneous biopsy procedures of head and neck lesions using 0.23T open MRI with optical tracking.
A retrospective analysis of 77 patients (51 male, 26 female; mean age, 43 years; range, 11-88 years) who underwent MRI-guided percutaneous biopsy of a head and neck lesion was performed. Mean lesion diameter was 3 cm (range, 1-7.8 cm). Rapid gradient echo sequences were used for image guidance. 23/77 lesions were biopsied after intravenous gadolinium. Tissue sampling techniques included needle aspiration (n = 19) and core needle biopsy (n = 58). Outcome variables included technical success, diagnostic accuracy, procedure time and complications.
In all patients, a sufficient amount of tissue for pathological analysis was obtained. Pathological analysis diagnosed 41 malignant lesions and 36 benign lesions. In 42 cases, surgical correlation was available. In 35 cases, the final diagnosis was confirmed by imaging and clinical follow-up. MR-guided biopsy had a sensitivity, specificity, positive predictive value, negative predictive value and accuracy of 93.2%, 100%, 100%, 91.7%, and 96%, respectively. Procedure time was 29 min (range, 15-47 min). No major complications occurred.
MRI-guided biopsy of head and neck lesions has a high diagnostic performance and is safe in clinical practice.
• MRI-guided biopsy helps clinicians to assess patients with head&neck masses. • Differention of malignant and benign lesions is possible with 96% accuracy. • The safety profile of MRI-guided biopsy of head&neck lesions is favorable. • MRI guidance enables accurate biopsy without the use of ionizing radiation.
评估使用光学跟踪 0.23T 开放式 MRI 对头部和颈部病变进行 MRI 引导经皮活检的疗效和安全性。
回顾性分析了 77 例（男 51 例，女 26 例；平均年龄 43 岁；年龄范围 11-88 岁）接受头部和颈部病变 MRI 引导经皮活检的患者。平均病变直径为 3cm（范围 1-7.8cm）。快速梯度回波序列用于图像引导。23/77 例病变在静脉注射钆后进行活检。组织取样技术包括针吸（n=19）和芯针活检（n=58）。主要观察指标包括技术成功率、诊断准确性、操作时间和并发症。
所有患者均获得了足够用于病理分析的组织量。病理分析诊断出 41 例恶性病变和 36 例良性病变。42 例患者有手术相关性。35 例患者的最终诊断通过影像学和临床随访得到证实。MR 引导活检的敏感性、特异性、阳性预测值、阴性预测值和准确性分别为 93.2%、100%、100%、91.7%和 96%。操作时间为 29 分钟（范围 15-47 分钟）。无重大并发症发生。
MRI 引导的头颈部病变活检具有较高的诊断性能，在临床实践中是安全的。
MRI 引导活检有助于临床医生评估头颈部肿块患者。
96%的准确率可区分恶性和良性病变。
MRI 引导头颈部病变活检的安全性良好。
MRI 引导可实现精准活检，无需使用电离辐射。
