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针对癌症中的 PI3K/mTOR 信号通路。

Targeting PI3K/mTOR signaling in cancer.

机构信息

Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA.

出版信息

Cancer Res. 2011 Dec 15;71(24):7351-9. doi: 10.1158/0008-5472.CAN-11-1699. Epub 2011 Oct 10.

Abstract

The American Association for Cancer Research (AACR) Special Conference on Targeting PI3K/mTOR Signaling in Cancer was held in San Francisco, California from February 24 to 27, 2011. The meeting was cochaired by Drs. Lewis C. Cantley, David M. Sabatini, and Funda Meric-Bernstam. The main focus of this event was the therapeutic potential of drugs targeting the PI3K/mTOR signaling pathway for the treatment of cancer. This article summarizes the recent discoveries in the field, with particular emphasis on the major themes of the conference.

摘要

美国癌症研究协会(AACR)于 2011 年 2 月 24 日至 27 日在加利福尼亚州旧金山举行了靶向癌症中 PI3K/mTOR 信号的特别会议。会议由 Lewis C. Cantley、David M. Sabatini 和 Funda Meric-Bernstam 博士共同主持。本次活动的主要重点是针对 PI3K/mTOR 信号通路的药物的治疗潜力,用于治疗癌症。本文总结了该领域的最新发现,特别强调了会议的主要主题。

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