Veterinary Public Health Consultants, Research Institute for Tropical Medicine, Muntinlupa City, Philippines.
J Infect Dis. 2011 Nov;204 Suppl 3:S757-60. doi: 10.1093/infdis/jir296.
The 2008 Reston ebolavirus infection event in domestic pigs has triggered continuing epidemiologic investigations among Philippine health and veterinary agencies in collaboration with international filovirus experts. Prior to this, there were only 3 known and documented Reston ebolavirus outbreaks in nonhuman primates in the world, all traced back to a single geographic source in the Philippines in a monkey breeding/export facility. The first one in 1989 was the first-ever Ebola virus that emerged outside of Africa and was also the first known natural infection of Ebola virus in nonhuman primates. When it was first discovered among laboratory monkeys in the United States, the source was immediately traced back to the farm located in the Philippines. The second outbreak was in 1992-93. The third episode in 1996 was the last known outbreak before Reston ebolavirus reemerged in pigs in 2008. The isolated outbreaks involving 2 animal species bring forth issues requiring further investigations, and highlight the significance of intersectoral collaboration to effectively address zoonoses prevention and control/response in the interest of minimizing public health risk.
2008 年，在菲律宾国内猪群中发生的雷斯顿埃博拉病毒感染事件促使菲律宾卫生和兽医机构与国际丝状病毒专家合作，持续开展流行病学调查。在此之前，全世界仅有 3 起已知并记录在案的非人灵长类动物雷斯顿埃博拉病毒暴发事件，均可追溯到菲律宾一个猴子繁殖/出口设施中的单一地理来源。首次暴发于 1989 年，是首次在非洲以外出现的埃博拉病毒，也是首例已知的非人类灵长类动物中埃博拉病毒的自然感染。当它首次在美国实验室猴子中被发现时，其源头立即被追溯到位于菲律宾的农场。第二次暴发发生在 1992-93 年。第三次发生在 1996 年，是 2008 年雷斯顿埃博拉病毒重新在猪群中出现之前的最后一次已知暴发。这两起涉及两种动物物种的孤立暴发事件引发了需要进一步调查的问题，并强调了部门间合作的重要性，以便有效应对人畜共患病的预防、控制和应对，最大限度地降低公共卫生风险。
