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增加少数民族参与药物滥用临床试验:国家药物滥用研究所临床试验网络的经验教训。

Increasing ethnic minority participation in substance abuse clinical trials: lessons learned in the National Institute on Drug Abuse's Clinical Trials Network.

机构信息

Department of Psychology, University of Cincinnati, OH 45221, USA.

出版信息

Cultur Divers Ethnic Minor Psychol. 2011 Oct;17(4):345-56. doi: 10.1037/a0025668.

DOI:10.1037/a0025668
PMID:21988575
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3427793/
Abstract

Underrepresentation in clinical trials limits the extent to which ethnic minorities benefit from advances in substance abuse treatment. The objective of this article is to share the knowledge gained within the Clinical Trials Network (CTN) of the National Institute on Drug Abuse and other research on recruiting and retaining ethnic minorities into substance abuse clinical trials. The article includes a discussion of two broad areas for improving inclusion-community involvement and cultural adaptation. CTN case studies are included to illustrate three promising strategies for improving ethnic minority inclusion: respondent-driven sampling, community-based participatory research, and the cultural adaptation of the recruitment and retention procedures. The article concludes with two sections describing a number of methodological concerns in the current research base and our proposed research agenda for improving ethnic minority inclusion that builds on the CTN experience.

摘要

在临床试验中代表性不足限制了少数族裔从物质滥用治疗的进步中受益的程度。本文的目的是分享国家药物滥用研究所临床试验网络(CTN)和其他研究在招募和保留少数民族参与物质滥用临床试验方面获得的知识。本文包括讨论两个改善纳入的广泛领域——社区参与和文化适应。CTN 案例研究包括说明三种有前途的策略,以提高少数民族的包容性:响应驱动抽样、基于社区的参与式研究以及招募和保留程序的文化适应。本文最后两节描述了当前研究基础中的一些方法学问题,以及我们提出的改善少数民族包容性的研究议程,该议程建立在 CTN 经验的基础上。

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Psychotherapy (Chic). 2006 Winter;43(4):531-48. doi: 10.1037/0033-3204.43.4.531.
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Motivational enhancement therapy for African American substance users: a randomized clinical trial.动机增强疗法治疗非裔美国物质使用者:一项随机临床试验。
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J Consult Clin Psychol. 2011 Dec;79(6):713-27. doi: 10.1037/a0025477. Epub 2011 Oct 3.
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