Department of Neurology, Klinikum Darmstadt, Darmstadt, Germany.
J Neurointerv Surg. 2010 Mar;2(1):59-64. doi: 10.1136/jnis.2009.000836. Epub 2009 Dec 4.
Carotid artery stenting was carried out in a prospective consecutive case study. All interventions were done by the same investigator (PH), and one type of stenting device was used. Additionally, periprocedural monitoring was carried out for at least 24 h. 190 patients were included (70±8.9 years). All had a high grade stenosis (>70% according to North American Symptomatic Carotid Endarterectomy Trial (NASCET) criteria). 140 were men and 50 were women. 104 (55%) had symptomatic stenosis and 86 (45%) had asymptomatic stenosis. A self-expanding nitinol-carotis stent was used (Cordis Precise stent; Johnson and Johnson) with an emboli capture guidewire basket system (Angioguard; Cordis). 30 day complications (infarct, hemorrhage, death due to either) were seen in 13 cases (6.8%). Disabling complications with an increase in the modified Rankin Scale by >2 points after 6 months were seen in five cases (2.6%). The rate of complications after carotid artery stenting was comparable with that after carotid endarterectomy (from the literature). No correlation was seen between complications and age, gender, diabetes, hypertension, symptomatic stenosis or plaque morphology. This may be because of the the 24 h post-procedural monitoring.
颈动脉支架置入术是一项前瞻性连续病例研究。所有干预措施均由同一位研究者（PH）进行，使用了一种支架置入装置。此外，至少进行了 24 小时的围手术期监测。共纳入 190 例患者（70±8.9 岁）。所有患者均存在高度狭窄（根据北美症状性颈动脉内膜切除术试验（NASCET）标准，狭窄程度>70%）。140 例为男性，50 例为女性。104 例（55%）为有症状性狭窄，86 例（45%）为无症状性狭窄。使用了一种自膨式镍钛合金颈动脉支架（Cordis Precise 支架；Johnson and Johnson）和一种带血栓捕获导丝篮系统（Angioguard；Cordis）。30 天并发症（梗死、出血、因任何原因导致的死亡）发生在 13 例（6.8%）。6 个月后改良 Rankin 量表评分增加>2 分的致残性并发症发生在 5 例（2.6%）。颈动脉支架置入术后的并发症发生率与颈动脉内膜切除术（来自文献）相当。并发症与年龄、性别、糖尿病、高血压、症状性狭窄或斑块形态之间无相关性。这可能是由于术后 24 小时的监测。
