Suppr超能文献

老年炎症性肠病:警钟敲响。

Inflammatory bowel disease of the elderly: a wake-up call.

作者信息

Katz Seymour, Feldstein Richard

机构信息

Dr. Katz serves as Clinical Professor of Medicine at the New York University School of Medicine in New York, New York, and as an Attending Gastroenterologist at North Shore University Hospital-Long Island Jewish Medical Center in Manhasset, New York.

出版信息

Gastroenterol Hepatol (N Y). 2008 May;4(5):337-47.

Abstract

As the baby-boomer generation enters the ranks of the elderly (defined as patients over 60 years of age), the increased burden of managing older inflammatory bowel disease (IBD) patients requires recognition of the impact of comorbid disease, polypharmacy, and surgical candidacy criteria. There is a surprisingly positive response to newer therapies and surgery, provided that a distinction is made between "fit elderly" and "frail elderly" patients. The former group should not be denied access to the newer biologics, clinical trials, or surgical alternatives on the basis of age alone. There is a need for clinicians caring for elderly IBD patients to be cognizant of the multiple and often disguised conditions contributing to disease management as well as the importance for careful allocation of health resources.

摘要

随着婴儿潮一代步入老年(定义为60岁以上的患者),管理老年炎症性肠病(IBD)患者的负担日益加重,这就需要认识到合并症、多种药物治疗以及手术候选标准的影响。只要区分“健康老年人”和“体弱老年人”患者,对新疗法和手术就会有出人意料的积极反应。不应仅基于年龄而拒绝前一组患者使用新型生物制剂、参加临床试验或选择手术替代方案。照顾老年IBD患者的临床医生需要认识到导致疾病管理的多种且常常隐匿的状况,以及谨慎分配医疗资源的重要性。

相似文献

3
Therapeutic challenges of managing inflammatory bowel disease in the elderly patient.老年炎症性肠病患者治疗面临的挑战。
Expert Rev Gastroenterol Hepatol. 2016 Sep;10(9):1005-10. doi: 10.1080/17474124.2016.1179579. Epub 2016 Apr 28.
9
Drug Management in the Elderly IBD Patient.老年炎症性肠病患者的药物管理
Curr Treat Options Gastroenterol. 2015 Mar;13(1):90-104. doi: 10.1007/s11938-014-0039-2.

引用本文的文献

4
Immunomodulation in age-related disorders and nanotechnology interventions.与年龄相关的疾病的免疫调节和纳米技术干预。
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2023 Jan;15(1):e1840. doi: 10.1002/wnan.1840. Epub 2022 Aug 10.
8
Special Considerations for Colorectal Surgery in the Elderly IBD Patient.老年炎症性肠病患者结直肠手术的特殊考量
Curr Treat Options Gastroenterol. 2019 Dec;17(4):449-456. doi: 10.1007/s11938-019-00254-1.

本文引用的文献

2
Drug interactions in inflammatory bowel disease.炎症性肠病中的药物相互作用。
Am J Gastroenterol. 2008 Jan;103(1):207-19; quiz 206, 220. doi: 10.1111/j.1572-0241.2007.01559.x. Epub 2007 Dec 11.
4
Dose-dependent influence of 5-aminosalicylates on thiopurine metabolism.5-氨基水杨酸酯对硫嘌呤代谢的剂量依赖性影响。
Am J Gastroenterol. 2007 Dec;102(12):2747-53. doi: 10.1111/j.1572-0241.2007.01511.x. Epub 2007 Aug 31.
8
Problems encountered during anti-tumour necrosis factor therapy.抗肿瘤坏死因子治疗期间遇到的问题。
Best Pract Res Clin Rheumatol. 2006 Aug;20(4):757-90. doi: 10.1016/j.berh.2006.06.002.
10
Clinically relevant drug interactions with antiepileptic drugs.抗癫痫药物的临床相关药物相互作用。
Br J Clin Pharmacol. 2006 Mar;61(3):246-55. doi: 10.1111/j.1365-2125.2005.02529.x.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验