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[促黄体素释放激素的心脏效应。促黄体素释放激素对磷酸化酶A和鸟氨酸脱羧酶活性以及3',5'-腺苷酸浓度的影响]

[Cardiotropic effects of luliberin. Effects of luliberin on the activities of phosphorylase A and ornithine decarboxylase and concentration of 3', 5'-AMP].

作者信息

Isachenkov V A, Bakalkin G Ia, Iatygin K N, Komissarova E N, Tsibezov V V

出版信息

Biokhimiia. 1979 Feb;44(2):233-9.

PMID:219912
Abstract

The level of luliberin, the luteinizing hormone-releasing hormone (LH-RH), and the possibility of the hormonal control of metabolic and biosynthetic processes in the heart were studied. It was shown that the rat heart contains a factor, which is immunochemically and chromatographically related to LH-RH (19--46 picograms per organ). Intraperitoneal injection of LH-RH increases the activities of phosphorylase A and ornithine decarboxylase and the concentration of 3',5'-AMP and potentiates the stimulating effect of adrenaline on ornithine decarboxylase.

摘要

研究了促黄体素释放激素(LH-RH)即促性腺激素释放激素的水平,以及心脏中代谢和生物合成过程受激素控制的可能性。结果表明,大鼠心脏含有一种因子,该因子在免疫化学和色谱方面与LH-RH相关(每个器官含19 - 46皮克)。腹腔注射LH-RH可增加磷酸化酶A和鸟氨酸脱羧酶的活性、3',5'-AMP的浓度,并增强肾上腺素对鸟氨酸脱羧酶的刺激作用。

相似文献

1
[Cardiotropic effects of luliberin. Effects of luliberin on the activities of phosphorylase A and ornithine decarboxylase and concentration of 3', 5'-AMP].[促黄体素释放激素的心脏效应。促黄体素释放激素对磷酸化酶A和鸟氨酸脱羧酶活性以及3',5'-腺苷酸浓度的影响]
Biokhimiia. 1979 Feb;44(2):233-9.
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Regulation of rat heart ornithine decarboxylase: change in affinity for ornithine evoked by neuronal, hormonal, and ontogenetic stimuli.大鼠心脏鸟氨酸脱羧酶的调节:神经元、激素和个体发育刺激引起的对鸟氨酸亲和力的变化。
Mol Pharmacol. 1979 Sep;16(2):504-12.
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Temporal changes in ovarian ornithine decarboxylase and cyclic AMP in immature rats stimulated by exogenous or endogenous gonadotrophins.外源性或内源性促性腺激素刺激下未成熟大鼠卵巢中鸟氨酸脱羧酶和环磷酸腺苷的时间变化。
J Endocrinol. 1977 Jun;73(3):463-71. doi: 10.1677/joe.0.0730463.
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Desensitization of testicular ornithine decarboxylase to gonadotropin releasing hormone and gonadotropic hormones.
Biochem Int. 1985 Aug;11(2):225-32.
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[Cardiotropic effects of luliberin. Interaction with rat heart sarcolemmal membrane].
Biokhimiia. 1979 Mar;44(3):387-93.
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Alteration in cyclic AMP-dependent protein kinases and polyamine biosynthetic enzymes during hypertrophy and hyperplasia of the thyroid in the rat.大鼠甲状腺肥大和增生过程中环磷酸腺苷依赖性蛋白激酶和多胺生物合成酶的变化。
Mol Pharmacol. 1983 May;23(3):641-7.
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[Effect of luliberin on the Ca-accumulating capacity of the myocardial membranes of the rat heart].[促黄体素释放素对大鼠心肌膜钙蓄积能力的影响]
Biull Eksp Biol Med. 1980 Aug;90(8):135-7.
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Selective loss of ornithine decarboxylase response to adrenergic agonists and glucagon during food deprivation of neonatal rats.新生大鼠饥饿期间鸟氨酸脱羧酶对肾上腺素能激动剂和胰高血糖素反应的选择性丧失。
J Pharmacol Exp Ther. 1983 Apr;225(1):50-6.
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Stimulation of ornithine decarboxylase activity by luteinizing hormone releasing hormone in the testis of immature rat.
Biochem Biophys Res Commun. 1982 Nov 16;109(1):269-74. doi: 10.1016/0006-291x(82)91595-9.
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Some properties of rat myocardial ornithine decarboxylase and the in vitro effects of nucleotides.大鼠心肌鸟氨酸脱羧酶的一些特性及核苷酸的体外效应
Recent Adv Stud Cardiac Struct Metab. 1975;7:77-83.

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Effects of gonadotrophin-releasing hormone outside the hypothalamic-pituitary-reproductive axis.促性腺激素释放激素在下丘脑-垂体-生殖轴之外的作用。
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