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[促黄体素释放激素的心脏效应。促黄体素释放激素对磷酸化酶A和鸟氨酸脱羧酶活性以及3',5'-腺苷酸浓度的影响]

[Cardiotropic effects of luliberin. Effects of luliberin on the activities of phosphorylase A and ornithine decarboxylase and concentration of 3', 5'-AMP].

作者信息

Isachenkov V A, Bakalkin G Ia, Iatygin K N, Komissarova E N, Tsibezov V V

出版信息

Biokhimiia. 1979 Feb;44(2):233-9.

PMID:219912
Abstract

The level of luliberin, the luteinizing hormone-releasing hormone (LH-RH), and the possibility of the hormonal control of metabolic and biosynthetic processes in the heart were studied. It was shown that the rat heart contains a factor, which is immunochemically and chromatographically related to LH-RH (19--46 picograms per organ). Intraperitoneal injection of LH-RH increases the activities of phosphorylase A and ornithine decarboxylase and the concentration of 3',5'-AMP and potentiates the stimulating effect of adrenaline on ornithine decarboxylase.

摘要

研究了促黄体素释放激素(LH-RH)即促性腺激素释放激素的水平,以及心脏中代谢和生物合成过程受激素控制的可能性。结果表明,大鼠心脏含有一种因子,该因子在免疫化学和色谱方面与LH-RH相关(每个器官含19 - 46皮克)。腹腔注射LH-RH可增加磷酸化酶A和鸟氨酸脱羧酶的活性、3',5'-AMP的浓度,并增强肾上腺素对鸟氨酸脱羧酶的刺激作用。

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